Tandem Michael Addition/Imino-Nitrile Cyclization Synthesis of 2-Amino-6-(1-aryl-5-methyl-1H-1,2,3-triazol-4yl)-4-phenylpyridine-3-carbonitrile

被引：15

作者：

Dong, Hene-Shan ^{[1
]}

Wang, Hui-Cheng ^{[1
]}

Gao, Zhone-Lian ^{[1
]}

Li, Rong-Shan ^{[1
]}

Cui, Fu-Hong ^{[1
]}

机构：

[1] Lanzhou Univ, Inst Organ Chem, State Key Lab Appl Organ Chem, Coll Chem & Chem Engn, Lanzhou 730000, Gansu, Peoples R China

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2010年 / 47卷 / 02期

关键词：

CATALYZED AMINATION; ARYL CHLORIDES; COMPLEXES; LIGANDS; ANTAGONISTS; RECEPTOR;

D O I：

10.1002/jhet.336

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Several 2-amino-6-(1-aryl-5-methyl-1H-1,2,3-triazol-4-yl)-4-phenylpyridine-3-carbonitrile have been synthesized by Tandem Michael addition/imino-nitrile cyclization and the structures of these compounds were established by MS, IR, CHN, and (1)H NMR spectral data. The crystal structure of 2-amino-6-[1-(4-methoxyphenyl)-5-methyl-1H-1,2,3-triazol-4-yl]-4-phenylpyridine-3-carbonitrile was established by X-ray diffraction.

引用

页码：389 / 395

页数：7

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