Effect of dioxane on the hydration of human serum albumin as studied by isothermal calorimetry and IR spectroscopy

被引：3
|
作者：
Sirotkin, V. A. [1 ]
Korolev, D. V. [1 ]
机构：
[1] Kazan VI Lenin State Univ, Butlerov Inst Chem, Kazan, Tatarstan, Russia
来源：
RUSSIAN JOURNAL OF PHYSICAL CHEMISTRY | 2006年 / 80卷 / 05期
关键词：
D O I：
10.1134/S0036024406050256
中图分类号：
O64 [物理化学（理论化学）、化学物理学];
学科分类号：
070304 ; 081704 ;
摘要：
A comparison of isothermal calorimetry data on the interaction of human serum albumin with water in the presence and absence of dioxane and of the isotherms of adsorption of vapors of water and dioxane on HSA as measured by IR spectroscopy made it possible to suggest an experimental method for isolating the contribution from the organic solvent to the thermodynamic and sorption characteristics of hydration of the protein over the entire range of water activities.
引用
收藏
页码：809 / 814
页数：6
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