EPIDEMIOLOGICAL DATA ON THE NUTRITIONAL STATUS OF CANCER PATIENTS RECEIVING TREATMENT WITH CONCOMITANT CHEMORADIOTHERAPY, RADIOTHERAPY OR SEQUENTIAL CHEMORADIOTHERAPY TO THE ABDOMINOPELVIC AREA

被引:0
作者
Serralde-Zuniga, Aurora [1 ]
Castro-Eguiluz, Denisse [2 ]
Luis Aguilar-Ponce, Jose [3 ,4 ,5 ]
Andrea Pena-Ruiz, Angelica [3 ,4 ,5 ]
Victor Castro-Gutierrez, Jorge [3 ,4 ,5 ]
Rivera-Rivera, Samuel [6 ]
Aranda-Flores, Carlos [7 ]
Casique-Perez, Veronica [3 ,4 ,5 ,8 ]
Eugenia Alarcon-Barrios, Silvia [3 ,4 ,5 ]
de la Garza-Salazar, Jaime [3 ,4 ,5 ]
Sanchez-Lopez, Miriam [3 ,4 ,5 ]
Duenas-Gonzalez, Alfonso [9 ]
机构
[1] Inst Nacl Ciencias Med & Nutr Salvador Zubiran, Dept Nutr, Mexico City, DF, Mexico
[2] Inst Nacl Cancerol, Dept Clin Res, Consejo Nacl Ciencia & Tecnol CONACyT, Mexico City, DF, Mexico
[3] Inst Nacl Cancerol, Dept Internal Med, Mexico City, DF, Mexico
[4] Inst Nacl Cancerol, Dept Nutr, Mexico City, DF, Mexico
[5] Inst Nacl Cancerol, Dept Clin Res, Mexico City, DF, Mexico
[6] Soc Mexicana Oncol AC, Mexico City, DF, Mexico
[7] Consejo Mexicano Oncol AC, Mexico City, DF, Mexico
[8] Univ Autonoma Tlaxcala, Fac Ciencias Salud, Dept Nutr, Tlaxcala, Tlax, Mexico
[9] Univ Nacl Autonoma Mexico, Inst Nacl Cancerol, Inst Invest Biomed, Mexico City, DF, Mexico
来源
REVISTA DE INVESTIGACION CLINICA-CLINICAL AND TRANSLATIONAL INVESTIGATION | 2018年 / 70卷 / 03期
关键词
Epidemiology; Pelvic cancer; Radiotherapy; Chemotherapy; Nutritional status; Gastrointestinal toxicity; VAIZEY INCONTINENCE QUESTIONNAIRE; SUBJECTIVE GLOBAL ASSESSMENT; BOWEL-DISEASE QUESTIONNAIRE; PELVIC RADIOTHERAPY; COLORECTAL-CANCER; GASTROINTESTINAL SYMPTOMS; GYNECOLOGICAL CANCER; CERVICAL-CANCER; PHASE-ANGLE; MALNUTRITION;
D O I
10.24875/RIC.18002523
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Cancer patients are particularly susceptible to undernourishment so associated weight loss is frequent. Approximately 15% of patients lose >10% of their usual body weight, 40-80% become undernourished, and about 20% die as a result. Well-nourished patients have a higher survival rate when compared with patients at risk of undernourishment (19.9 vs. 3.7 months); hence, nutritional intervention is pivotal. Undernourishment negatively influences the patient's prognosis, and its prevalence depends on the tumor type and location, disease stage, treatment, and the applied nutritional evaluation tool. During abdominopelvic radiotherapy, up to 90% of patients experience symptoms of varying severity; weight loss during radiotherapy is an early indicator of nutritional deterioration, and he the use of radiation is associated with a higher likelihood of undernourishment. In patients with gynecological malignancies, 12.5-54% are malnourished before receiving oncological treatment, worsening after treatment in 35.8-82% of cases. There is also deterioration of the nutritional status in patients with colorectal cancer once pelvic radiotherapy is initiated, whereby 50% of cases are malnourished at the beginning of treatment, and 66.7% are so when it ends. Although there are notable differences in the impact of radiotherapy on weight according to the radiated region, 88% patients receiving abdominal radiotherapy were found to lose weight compared to 38% of patients whose treatment was limited to the pelvis.
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页码:117 / 120
页数:4
相关论文
共 32 条
  • [11] Review of American Society for Parenteral and Enteral Nutrition (ASPEN) Clinical Guidelines for Nutrition Support in Cancer Patients: Nutrition Screening and Assessment
    Huhmann, Maureen B.
    August, David A.
    [J]. NUTRITION IN CLINICAL PRACTICE, 2008, 23 (02) : 182 - 188
  • [12] Validity of the malnutrition screening tool as an effective predictor of nutritional risk in oncology outpatients receiving chemotherapy
    Isenring, Elisabeth
    Cross, Giordana
    Daniels, Lynne
    Kellett, Elizabeth
    Koczwara, Bogda
    [J]. SUPPORTIVE CARE IN CANCER, 2006, 14 (11) : 1152 - 1156
  • [13] A modified Inflammatory Bowel Disease Questionnaire and the Vaizey Incontinence questionnaire are more sensitive measures of acute gastrointestinal toxicity during pelvic radiotherapy than RTOG grading
    Khalid, U
    McGough, C
    Hackett, C
    Blake, P
    Harrington, KJ
    Khoo, VS
    Tait, D
    Norman, AR
    Andreyev, HJN
    [J]. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2006, 64 (05): : 1432 - 1441
  • [14] The Effects of Body Mass Index on Complications and Survival Outcomes in Patients With Cervical Carcinoma Undergoing Curative Chemoradiation Therapy
    Kizer, Nora T.
    Thaker, Premal H.
    Gao, Feng
    Zighelboim, Israel
    Powell, Matthew A.
    Rader, Janet S.
    Mutch, David G.
    Grigsby, Perry W.
    [J]. CANCER, 2011, 117 (05) : 948 - 956
  • [15] Malnutrition among gynaecological cancer patients
    Laky, B.
    Janda, M.
    Bauer, J.
    Vavra, C.
    Cleghorn, G.
    Obermair, A.
    [J]. EUROPEAN JOURNAL OF CLINICAL NUTRITION, 2007, 61 (05) : 642 - 646
  • [16] Altered plasma phospholipid fatty acids and nutritional status in patients with uterine cervical cancer
    Lisboa, Adriana Q.
    Rezende, Marilia
    Muniz-Junqueira, Maria I.
    Ito, Marina K.
    [J]. CLINICAL NUTRITION, 2008, 27 (03) : 371 - 377
  • [17] Mahdavi R, 2007, SAUDI MED J, V28, P435
  • [18] Role of nutritional intervention in patients treated with radiotherapy for pelvic malignancy
    McGough, C
    Baldwin, C
    Frost, G
    Andreyev, HJN
    [J]. BRITISH JOURNAL OF CANCER, 2004, 90 (12) : 2278 - 2287
  • [19] An inflammation-based prognostic score and its role in the nutrition-based management of patients with cancer
    McMillan, Donald C.
    [J]. PROCEEDINGS OF THE NUTRITION SOCIETY, 2008, 67 (03) : 257 - 262
  • [20] Depression and appetite: predictors of malnutrition in gynecologic cancer
    Nho, Ju-Hee
    Kim, Sung Reul
    Kwon, Yong Soon
    [J]. SUPPORTIVE CARE IN CANCER, 2014, 22 (11) : 3081 - 3088