Severe influenza in a paediatric patient with GATA2 deficiency and Emberger syndrome

被引：1
|
作者：
Jensen, Marie Louise Naestholt [1 ,2 ]
Mathiasen, Victor Dahl [3 ]
Ifversen, Marinne [1 ,4 ]
Nielsen, Jeppe Sylvest Angaard [1 ,5 ]
机构：
[1] Rigshosp, Copenhagen Univ Hosp, Dept Paediat & Adolescent Med, Copenhagen, Denmark
[2] Aarhus Univ Hosp, Dept Rheumatol, Aarhus N, Denmark
[3] Aarhus Univ Hosp, Dept Infect Dis, Aarhus N, Denmark
[4] Rigshosp, Copenhagen Univ Hosp, Dept Paediat & Adolescent Med, Bone Marrow Transplant Unit, Copenhagen, Denmark
[5] Rigshosp, Copenhagen Univ Hosp, Dept Intens Care Med, Copenhagen, Denmark
来源：
BMJ CASE REPORTS | 2020年 / 13卷 / 12期
关键词：
influenza; paediatric intensive care; paediatric surgery; paediatric oncology; MYELODYSPLASTIC SYNDROMES; SPORADIC MONOCYTOPENIA; AUTOSOMAL-DOMINANT; MUTATIONS; CHILDREN;
D O I：
10.1136/bcr-2020-236521
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A 9-year-old girl was admitted to the paediatric intensive care unit with acute respiratory failure due to influenza. Nine months earlier, she presented with unexplained lymphoedema of the lower extremities and monocytopenia. She had a history of occasional finger warts and onychomycoses. During hospitalisation, the patient was diagnosed with Emberger syndrome caused by GATA2 deficiency. The admission was complicated by thromboses in the right hand, leading to amputation of multiple fingers. From then on, the patient has been in good recovery, the function of her right hand was improving and an allogeneic haematopoietic cell transplantation has now been successfully performed.
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页数：4
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