Probiotics and prevention of Clostridium difficile infection

被引：30
|
作者：
Goldstein, E. J. C. [1 ,2 ]
Johnson, S. J. [3 ]
Maziade, P. -J. [4 ]
Evans, C. T. [5 ,6 ,7 ]
Sniffen, J. C. [8 ]
Millette, M. [9 ]
McFarland, L. V. [10 ]
机构：
[1] RM Alden Res Lab, Santa Monica, CA USA
[2] Univ Calif Los Angeles, Sch Med, Los Angeles, CA USA
[3] Loyola Sch Med, Chicago, IL USA
[4] Pierre Le Gardeur Hosp, Terrebonne, PQ, Canada
[5] Northwestern Univ, Dept Prevent Med, Chicago, IL 60611 USA
[6] Northwestern Univ, Ctr Healthcare Studies, Chicago, IL 60611 USA
[7] Edward Hines Jr VA Hosp, Chicago, IL USA
[8] Florida Hosp, Orlando, FL USA
[9] BioK Plus Int Inc, Laval, PQ, Canada
[10] Univ Washington, Dept Med Chem, Seattle, WA 98195 USA
来源：
ANAEROBE | 2017年 / 45卷
关键词：
Probiotic; Bio-K; Saccharomyces boulardii; C; difficile; Lactobacillus rhamnosus GG; Lactobacillus acidophilus CL1285; Lactobacillus casei LBC80R; Lactobacillus rhamnosus CLR2; LACTOBACILLUS-ACIDOPHILUS CL1285; ANTIBIOTIC-ASSOCIATED DIARRHEA; CASEI LBC80R; COST-EFFECTIVENESS; DOUBLE-BLIND; COMBINATION; EPIDEMIOLOGY; INPATIENTS; SURVIVAL; RELAPSE;
D O I：
10.1016/j.anaerobe.2016.12.007
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The role of probiotics as adjunctive measures in the prevention of Clostridium difficile infection (CDI) has been controversial. However, a growing body of evidence has suggested that they have a role in primary prevention of CDI. Elements of this controversy are reviewed and the proposed mechanisms of action, the value and cost effectiveness of probiotics are addressed with a focus on three agents, Saccharomyces boulardii, Lactobacillus rhamnosus GG and the combination of Lactobacillus acidophilus CL1285, Lactobacillus casei LBC8OR, Lactobacillus rhamnosus CLR2 (Bio-K+). (C) 2016 Elsevier Ltd. All rights reserved.
引用
收藏
页码：114 / 119
页数：6
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