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Probiotics and prevention of Clostridium difficile infection
被引:30
|作者:
Goldstein, E. J. C.
[1
,2
]
Johnson, S. J.
[3
]
Maziade, P. -J.
[4
]
Evans, C. T.
[5
,6
,7
]
Sniffen, J. C.
[8
]
Millette, M.
[9
]
McFarland, L. V.
[10
]
机构:
[1] RM Alden Res Lab, Santa Monica, CA USA
[2] Univ Calif Los Angeles, Sch Med, Los Angeles, CA USA
[3] Loyola Sch Med, Chicago, IL USA
[4] Pierre Le Gardeur Hosp, Terrebonne, PQ, Canada
[5] Northwestern Univ, Dept Prevent Med, Chicago, IL 60611 USA
[6] Northwestern Univ, Ctr Healthcare Studies, Chicago, IL 60611 USA
[7] Edward Hines Jr VA Hosp, Chicago, IL USA
[8] Florida Hosp, Orlando, FL USA
[9] BioK Plus Int Inc, Laval, PQ, Canada
[10] Univ Washington, Dept Med Chem, Seattle, WA 98195 USA
来源:
关键词:
Probiotic;
Bio-K;
Saccharomyces boulardii;
C;
difficile;
Lactobacillus rhamnosus GG;
Lactobacillus acidophilus CL1285;
Lactobacillus casei LBC80R;
Lactobacillus rhamnosus CLR2;
LACTOBACILLUS-ACIDOPHILUS CL1285;
ANTIBIOTIC-ASSOCIATED DIARRHEA;
CASEI LBC80R;
COST-EFFECTIVENESS;
DOUBLE-BLIND;
COMBINATION;
EPIDEMIOLOGY;
INPATIENTS;
SURVIVAL;
RELAPSE;
D O I:
10.1016/j.anaerobe.2016.12.007
中图分类号:
Q93 [微生物学];
学科分类号:
071005 ;
100705 ;
摘要:
The role of probiotics as adjunctive measures in the prevention of Clostridium difficile infection (CDI) has been controversial. However, a growing body of evidence has suggested that they have a role in primary prevention of CDI. Elements of this controversy are reviewed and the proposed mechanisms of action, the value and cost effectiveness of probiotics are addressed with a focus on three agents, Saccharomyces boulardii, Lactobacillus rhamnosus GG and the combination of Lactobacillus acidophilus CL1285, Lactobacillus casei LBC8OR, Lactobacillus rhamnosus CLR2 (Bio-K+). (C) 2016 Elsevier Ltd. All rights reserved.
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页码:114 / 119
页数:6
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