Probiotics and prevention of Clostridium difficile infection

被引：30

作者：

Goldstein, E. J. C. ^{[1
,2
]}

Johnson, S. J. ^{[3
]}

Maziade, P. -J. ^{[4
]}

Evans, C. T. ^{[5
,6
,7
]}

Sniffen, J. C. ^{[8
]}

Millette, M. ^{[9
]}

McFarland, L. V. ^{[10
]}

机构：

[1] RM Alden Res Lab, Santa Monica, CA USA

[2] Univ Calif Los Angeles, Sch Med, Los Angeles, CA USA

[3] Loyola Sch Med, Chicago, IL USA

[4] Pierre Le Gardeur Hosp, Terrebonne, PQ, Canada

[5] Northwestern Univ, Dept Prevent Med, Chicago, IL 60611 USA

[6] Northwestern Univ, Ctr Healthcare Studies, Chicago, IL 60611 USA

[7] Edward Hines Jr VA Hosp, Chicago, IL USA

[8] Florida Hosp, Orlando, FL USA

[9] BioK Plus Int Inc, Laval, PQ, Canada

[10] Univ Washington, Dept Med Chem, Seattle, WA 98195 USA

来源：

ANAEROBE | 2017年 / 45卷

关键词：

Probiotic; Bio-K; Saccharomyces boulardii; C; difficile; Lactobacillus rhamnosus GG; Lactobacillus acidophilus CL1285; Lactobacillus casei LBC80R; Lactobacillus rhamnosus CLR2; LACTOBACILLUS-ACIDOPHILUS CL1285; ANTIBIOTIC-ASSOCIATED DIARRHEA; CASEI LBC80R; COST-EFFECTIVENESS; DOUBLE-BLIND; COMBINATION; EPIDEMIOLOGY; INPATIENTS; SURVIVAL; RELAPSE;

D O I：

10.1016/j.anaerobe.2016.12.007

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The role of probiotics as adjunctive measures in the prevention of Clostridium difficile infection (CDI) has been controversial. However, a growing body of evidence has suggested that they have a role in primary prevention of CDI. Elements of this controversy are reviewed and the proposed mechanisms of action, the value and cost effectiveness of probiotics are addressed with a focus on three agents, Saccharomyces boulardii, Lactobacillus rhamnosus GG and the combination of Lactobacillus acidophilus CL1285, Lactobacillus casei LBC8OR, Lactobacillus rhamnosus CLR2 (Bio-K+). (C) 2016 Elsevier Ltd. All rights reserved.

引用

页码：114 / 119

页数：6

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