The "Ice Age" in Cardiac Surgery: Evolution of the "Siberian" Method of Brain Protection During Deep Hypothermic Perfusionless Circulatory Arrest

被引：2

作者：

Guvakov, Dmitri ^{[1
,5
]}

Bezinover, Dmitri ^{[1
]}

Lomivorotov, Vladimir V. ^{[2
]}

Postnov, Vadim G. ^{[2
]}

Weiss, Stuart J. ^{[3
]}

Cheung, Albert T. ^{[4
]}

Swain, Julie ^{[5
]}

Lomivorotov, Vladimir N. ^{[2
]}

机构：

[1] Penn State Coll Med, Penn State Milton S Hershey Med Ctr, Dept Anesthesiol & Perioperat Med, Hershey, PA USA

[2] E Meshalkin Natl Med Res Ctr MNMRC, Dept Anesthesiol, Novosibirsk, Russia

[3] Univ Penn Hlth Syst, Dept Anesthesia & Crit Care, Philadelphia, PA USA

[4] Stanford Univ, Dept Anesthesiol Perioperat & Pain Med, Palo Alto, CA 94304 USA

[5] Mt Sinai Hlth Syst, Dept Clin Performance, New York, NY USA

来源：

JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA | 2019年 / 33卷 / 12期

关键词：

deep perfusion-less hypothermic circulatory arrest; cardio-pulmonary bypass; hypothermic brain protection; S-100-beta; neuron-specific enolase; meshalkin clinic; surface body cooling for cardiac surgery; hypothremic brain protection; luria battery; neurocognitive evaluation; OPEN-HEART-SURGERY; PROFOUND HYPOTHERMIA; COLD REPERFUSION; INFANTS; OPERATIONS;

D O I：

10.1053/j.jvca.2019.04.001

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

Deep hypothermic perfusionless circulatory arrest was the first practical neuroprotective technique used for open-heart surgery. It was refined at the Novosibirsk Medical Research Center in Siberia and was actively used from the mid-1950s until 2001. This review describes the development of this technique and its contribution to our understanding of the dynamic changes in human physiology during induced hypothermia for circulatory arrest without extracorporeal perfusion. Deep hypothermic perfusionless circulatory arrest was an important stepping stone in the development of modern approaches in neuroprotection and monitoring during cardiac surgery. (C) 2019 Elsevier Inc. All rights reserved.

引用

页码：3366 / 3374

页数：9

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