Diabetic kidney disease: a clinical update from Kidney Disease: Improving Global Outcomes

被引:219
作者
Molitch, Mark E. [1 ]
Adler, Amanda I. [2 ]
Flyvbjerg, Allan [3 ]
Nelson, Robert G. [4 ]
So, Wing-Yee [5 ]
Wanner, Christoph [6 ]
Kasiske, Bertram L. [7 ]
Wheeler, David C. [8 ]
de Zeeuw, Dick [9 ]
Mogensen, Carl E. [10 ,11 ]
机构
[1] Northwestern Univ, Feinberg Sch Med, Div Endocrinol, Chicago, IL 60611 USA
[2] Addenbrookes Hosp, Inst Metab Sci, Cambridge, England
[3] Aarhus Univ, Aarhus, Denmark
[4] NIDDK, NIH, Phoenix, AZ USA
[5] Chinese Univ Hong Kong, Dept Med & Therapeut, Hong Kong, Hong Kong, Peoples R China
[6] Univ Hosp Wurzburg, Wurzburg, Germany
[7] Hennepin Cty Med Ctr, Minneapolis, MN 55415 USA
[8] UCL, London, England
[9] Univ Groningen, Univ Med Ctr Groningen, NL-9713 AV Groningen, Netherlands
[10] Aarhus Univ Hosp, DK-8000 Aarhus, Denmark
[11] Aarhus Univ, Aarhus, Denmark
关键词
albuminuria; blood pressure; diabetic kidney disease; glycemic control; lipid management; GLOMERULAR-FILTRATION-RATE; BLOOD-PRESSURE CONTROL; CARDIORENAL END-POINTS; STAGE RENAL-DISEASE; HIGH VASCULAR RISK; GLYCEMIC CONTROL; CYSTATIN C; ALL-CAUSE; COLLABORATIVE METAANALYSIS; CARDIOVASCULAR MORTALITY;
D O I
10.1038/ki.2014.128
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
The incidence and prevalence of diabetes mellitus (DM) continue to grow markedly throughout the world, due primarily to the increase in type 2 DM (T2DM). Although improvements in DM and hypertension management have reduced the proportion of diabetic individuals who develop chronic kidney disease (CKD) and progress to end-stage renal disease (ESRD), the sheer increase in people developing DM will have a major impact on dialysis and transplant needs. This KDIGO conference addressed a number of controversial areas in the management of DM patients with CKD, including aspects of screening for CKD with measurements of albuminuria and estimated glomerular filtration rate (eGFR); defining treatment outcomes; glycemic management in both those developing CKD and those with ESRD; hypertension goals and management, including blockers of the renin-angiotensin-aldosterone system; and lipid management.
引用
收藏
页码:20 / 30
页数:11
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