Conversion of carbonimidodithioates into unsymmetrical di- and tri-substituted ureas including urea dipeptides

被引：20

作者：

Anbazhagan, M ^{[1
]}

Deshmukh, ARAS ^{[1
]}

Rajappa, S ^{[1
]}

机构：

[1] Natl Chem Lab, Div Organ Chem Synth, Pune 411008, Maharashtra, India

来源：

TETRAHEDRON LETTERS | 1998年 / 39卷 / 21期

关键词：

D O I：

10.1016/S0040-4039(98)00561-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Selective hydrolysis of carbonimidodithioates (3) leads to the thiocarbamates (4), which can be easily transformed to the unsymmetrical ureas (5) by treatment with the appropriate amines. This constitutes a synthesis of ureas without the use of phosgene or carbon monoxide. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：3609 / 3612

页数：4

共 15 条

[1] Conversion of carbonimidodithioates to carbamates [J].

Anbazhagan, M ;

Reddy, TI ;

Rajappa, S .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1997, (11) :1623-1627

[2] SYNTHESIS OF N,N'-DISUBSTITUTED UREAS FROM CARBAMATES [J].

BASHA, A .

TETRAHEDRON LETTERS, 1988, 29 (21) :2525-2526

[3] Synthesis of symmetrical and unsymmetrical ureas using unsymmetrical diaryl carbonates [J].

Freer, R ;

McKillop, A .

SYNTHETIC COMMUNICATIONS, 1996, 26 (02) :331-349

[4]

IZDEBSKI J, 1989, SYNTHESIS-STUTTGART, P423

[5] A general synthesis of unsymmetrical tetrasubstituted ureas [J].

Katritzky, AR ;

Pleynet, DPM ;

Yang, BZ .

JOURNAL OF ORGANIC CHEMISTRY, 1997, 62 (12) :4155-4158

[6]

Knolker HJ, 1996, SYNLETT, P502

[7] RUTHENIUM CATALYZED N,N'-DIARYLUREA SYNTHESIS FROM N-ARYL SUBSTITUTED FORMAMIDES AND AMINOARENES [J].

KOTACHI, S ;

TSUJI, Y ;

KONDO, T ;

WATANABE, Y .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1990, (07) :549-550

[8]

Lamothe M, 1996, SYNLETT, P507

[9] S,S-dimethyl dithiocarbonate: A convenient reagent for the synthesis of symmetrical and unsymmetrical ureas [J].

Leung, MK ;

Lai, JL ;

Lau, KH ;

Yu, HH ;

Hsiao, HJ .

JOURNAL OF ORGANIC CHEMISTRY, 1996, 61 (12) :4175-4179

[10] A SAFE AND EFFICIENT METHOD FOR PREPARATION OF N,N'-UNSYMMETRICALLY DISUBSTITUTED UREAS UTILIZING TRIPHOSGENE [J].

MAJER, P ;

RANDAD, RS .

JOURNAL OF ORGANIC CHEMISTRY, 1994, 59 (07) :1937-1938

← 1 2 →