Effect of glucose-insulin-potassium infusion on plasma free fatty acid concentrations in patients undergoing primary percutaneous coronary intervention for ST-elevation myocardial infarction

被引：10
作者：
Addo, TA
Keeley, EC
Cigarroa, JE
Lange, RA
de Lemos, JA
Dobbins, RL
McGuire, DK
机构：
[1] Univ Texas, SW Med Ctr, Dept Internal Med, Dallas, TX 75390 USA
[2] Univ Texas, SW Med Ctr, Donald W Reynolds Cardiovasc Clin Res Ctr, Dallas, TX USA
[3] Johns Hopkins Univ Hosp, Dept Internal Med, Baltimore, MD 21287 USA
[4] Johns Hopkins Univ Hosp, Donald W Reynolds Cardiovasc Clin Ctr, Baltimore, MD 21287 USA
[5] GlaxoSmithKline, Collegeville, PA USA
来源：
AMERICAN JOURNAL OF CARDIOLOGY | 2004年 / 94卷 / 10期
关键词：
D O I：
10.1016/j.amjcard.2004.07.115
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
To determine the effect of glucose-insulin-potassium infusion on circulating levels of free fatty acids in the setting of contemporary management of ST-elevation myocardial infarction, we randomly assigned 20 patients who were undergoing primary angioplasty to glucose-insulin-potassium infusion or to standard care. Treatment with glucose-insulin-potassium was associated with significantly lower levels of free fatty acid after 24 hours compared with standard care. (C) 2004 by Excerpta Medica, Inc.
引用
收藏
页码：1288 / 1289
页数：2
相关论文
共 8 条
[1]   Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review of 23 randomised trials [J].
Keeley, EC ;
Boura, JA ;
Grines, CL .
LANCET, 2003, 361 (9351) :13-20
[2]   EFFECTS OF GLUCOSE-INSULIN-POTASSIUM SOLUTION ON FREE FATTY-ACID METABOLISM IN ISCHEMIC MYOCARDIUM [J].
KOBAYASHI, A ;
KAMIYA, J ;
YAMASHITA, T ;
ISHIZAKA, K ;
HAYASHI, H ;
KAMIKAWA, T ;
YAMAZAKI, N .
JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION, 1984, 48 (06) :591-595
[3]   GLUCOSE-INSULIN-POTASSIUM INDUCED ALTERATIONS IN INDIVIDUAL PLASMA-FREE FATTY-ACIDS IN PATIENTS WITH ACUTE MYOCARDIAL-INFARCTION [J].
MCDANIEL, HG ;
PAPAPIETRO, SE ;
ROGERS, WJ ;
MANTLE, JA ;
SMITH, LR ;
RUSSELL, RO ;
RACKLEY, CE .
AMERICAN HEART JOURNAL, 1981, 102 (01) :10-15
[4]  
OLIVER MF, 1968, LANCET, V1, P710
[5]  
OPIE LH, 1977, LANCET, V2, P890
[6]   CLINICAL-EXPERIENCE WITH GLUCOSE-INSULIN-POTASSIUM THERAPY IN ACUTE MYOCARDIAL-INFARCTION [J].
RACKLEY, CE ;
RUSSELL, RO ;
ROGERS, WJ ;
MANTLE, JA ;
MCDANIEL, HG ;
PAPAPIETRO, SE .
AMERICAN HEART JOURNAL, 1981, 102 (06) :1038-1049
[7]   REDUCTION OF HOSPITAL MORTALITY-RATE OF ACUTE MYOCARDIAL-INFARCTION WITH GLUCOSE-INSULIN-POTASSIUM INFUSION [J].
ROGERS, WJ ;
STANLEY, AW ;
BREINIG, JB ;
PRATHER, JW ;
MCDANIEL, HG ;
MORASKI, RE ;
MANTLE, JA ;
RUSSELL, RO ;
RACKLEY, CE .
AMERICAN HEART JOURNAL, 1976, 92 (04) :441-454
[8]   PROSPECTIVE RANDOMIZED TRIAL OF GLUCOSE-INSULIN-POTASSIUM IN ACUTE MYOCARDIAL-INFARCTION - EFFECTS ON MYOCARDIAL HEMODYNAMICS, SUBSTRATES AND RHYTHM [J].
ROGERS, WJ ;
SEGALL, PH ;
MCDANIEL, HG ;
MANTLE, JA ;
RUSSELL, RO ;
RACKLEY, CE .
AMERICAN JOURNAL OF CARDIOLOGY, 1979, 43 (04) :801-809
1