Artificial recombination in forensic mtDNA population databases

被引:78
作者
Bandelt, HJ
Salas, A
Lutz-Bonengel, S
机构
[1] Univ Hamburg, Fachbereich Math, D-20146 Hamburg, Germany
[2] Fac Med, Inst Med Legal, Unidad Genet, Santiago De Compostela, Acoruna, Spain
[3] Univ Freiburg Klinikum, Inst Rechts Med, D-79104 Freiburg, Germany
关键词
mitochondrial DNA; error detection; recombination; networks;
D O I
10.1007/s00414-004-0455-2
中图分类号
DF [法律]; D9 [法律]; R [医药、卫生];
学科分类号
0301 ; 10 ;
摘要
Artificial recombination of two or more mitochondrial DNA fragments from different samples would constitute a serious cause of error in forensic DNA typing, and yet one can demonstrate that such events have happened in the preparation of several published mtDNA databases. Focussed database searches, phylogenetic analysis, and network representations can highlight mosaic patterns and thus pinpoint sample mix-up. Therefore, we suggest that this approach should be applied to data prior to publication in order to uncover such errors in time.
引用
收藏
页码:267 / 273
页数:7
相关论文
共 43 条
  • [21] Phylogeny of East Asian mitochondrial DNA lineages inferred from complete sequences
    Kong, QP
    Yao, YG
    Sun, C
    Bandelt, HJ
    Zhu, CL
    Zhang, YP
    [J]. AMERICAN JOURNAL OF HUMAN GENETICS, 2003, 73 (03) : 671 - 676
  • [22] Mitochondrial DNA sequence polymorphisms of five ethnic populations from northern China
    Kong, QP
    Yao, YG
    Liu, M
    Shen, SP
    Chen, C
    Zhu, CL
    Palanichamy, MG
    Zhang, YP
    [J]. HUMAN GENETICS, 2003, 113 (05) : 391 - 405
  • [23] Sequence variation of mitochondrial DNA control region in Koreans
    Lee, SD
    Shin, CH
    Kim, KB
    Lee, YS
    Lee, JB
    [J]. FORENSIC SCIENCE INTERNATIONAL, 1997, 87 (02) : 99 - 116
  • [24] Polymorphism in the mitochondrial cytochrome B gene in Koreans - An additional marker for individual identification
    Lee, SD
    Lee, YS
    Lee, JB
    [J]. INTERNATIONAL JOURNAL OF LEGAL MEDICINE, 2002, 116 (02) : 74 - 78
  • [25] Sequence polymorphisms within the human mitochondrial genes MTATP6, MTATPS and MTND4
    Lutz-Bonengel, S
    Schmidt, U
    Schmitt, T
    Pollak, S
    [J]. INTERNATIONAL JOURNAL OF LEGAL MEDICINE, 2003, 117 (03) : 133 - 142
  • [26] Malyarchuk BA, 2002, ANN HUM GENET, V66, P261, DOI 10.1017/S0003480002001161
  • [27] Sequence polymorphisms of the mitochondrial DNA control region and phylogenetic analysis of mtDNA lineages in the Japanese population
    Maruyama, S
    Minaguchi, K
    Saitou, N
    [J]. INTERNATIONAL JOURNAL OF LEGAL MEDICINE, 2003, 117 (04) : 218 - 225
  • [28] Miller KWP, 2001, CROAT MED J, V42, P315
  • [29] Natural selection shaped regional mtDNA variation in humans
    Mishmar, D
    Ruiz-Pesini, E
    Golik, P
    Macaulay, V
    Clark, AG
    Hosseini, S
    Brandon, M
    Easley, K
    Chen, E
    Brown, MD
    Sukernik, RI
    Olckers, A
    Wallace, DC
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (01) : 171 - 176
  • [30] Monson KL, 2002, FORENSIC SCI COMM, V4