Glucose-responsive polymer brushes for microcantilever sensing

被引：68

作者：

Chen, Tao ^{[1
,2
]}

Chang, Debby P. ^{[1
,2
]}

Liu, Ting ^{[4
]}

Desikan, Ramya ^{[3
]}

Datar, Ram ^{[5
]}

Thundat, Thomas ^{[3
]}

Berger, Ruediger ^{[4
]}

Zauscher, Stefan ^{[1
,2
]}

机构：

[1] Duke Univ, Ctr Biologically Inspired Mat & Mat Syst, Durham, NC 27708 USA

[2] Duke Univ, Dept Mech Engn & Mat Sci, Durham, NC 27708 USA

[3] Oak Ridge Natl Lab, Oak Ridge, TN 37831 USA

[4] Max Planck Inst Polymer Res, D-55128 Mainz, Germany

[5] Univ Miami, Biomed Nanosci Inst, Miami, FL 33136 USA

来源：

JOURNAL OF MATERIALS CHEMISTRY | 2010年 / 20卷 / 17期

基金：

美国国家科学基金会;

关键词：

N-ISOPROPYLACRYLAMIDE; CANTILEVER SENSORS; PHYSIOLOGICAL PH; ACTUATION; NANOPATTERNS; LITHOGRAPHY; TEMPERATURE; FABRICATION; SURFACES; RELEASE;

D O I：

10.1039/b925583d

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Glucose responsive polymer brushes were synthesized on gold substrates and microcantilever arrays. The response properties of these brushes were evaluated by exposing them to different glucose concentrations for a range of pH values. This work demonstrates the potential for polymer brush-functionalized micromechanical cantilevers as glucose detectors. Furthermore, the work demonstrates that stimulus-responsive polymer brushes on micromechanical cantilevers have a significantly larger bending response due to glucose binding compared with self-assembled monolayers.

引用

页码：3391 / 3395

页数：5

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