Chondrogenesis. of human mesenchymal stem cells

被引：0

作者：

Ito, T ^{[1
]}

Hattori, T ^{[1
]}

Amano, K ^{[1
]}

Nakano, A ^{[1
]}

Kamakura, M ^{[1
]}

机构：

[1] Teikyo Univ, Sch Med, Tokyo 173, Japan

来源：

7TH ANNUAL MEETING OF THE EUROPEAN HAEMATOLOGY ASSOCIATION | 2002年

关键词：

D O I：

暂无

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Bone marrow mesenchymal stem cells (MSCs) were tested their ability to undergo chondrogenesis. MSCs in a dish or a tube culture, treated with TGF-beta3 followed by thyroxine, expressed the morphology and histochemistry of cartilagenous tissues. Pellets grown in tube culture stained more intensely by alcian-blue, safranin-O, and azan-mallory. The factors to promote chondrogenesis were; tube culture, hypoxic culture, high-glucose DMEM, TGF-beta3, thyroxine, and dexamethasone. MSC-based cell therapy might be applicable for cartilage repair.

引用

页码：39 / 42

页数：4

共 3 条

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