The Introduction of Innovations in Neurovascular Care: Patient Selection and Randomized Allocation

被引：20

作者：

Fahed, Robert ^{[1
,2
]}

Darsaut, Tim E. ^{[3
]}

Raymond, Jean ^{[2
]}

机构：

[1] Rothschild Fdn Hosp, Dept Intervent Neuroradiol, Paris, France

[2] Ctr Hosp Univ Montreal, Notre Dame Hosp, Dept Radiol, Serv Neuroradiol, Montreal, PQ, Canada

[3] Univ Alberta Hosp, Mackenzie Hlth Sci Ctr, Dept Surg, Div Neurosurg, Edmonton, AB, Canada

来源：

WORLD NEUROSURGERY | 2018年 / 118卷

关键词：

Device; Ethics; Flow Diverter; Methodology; UNRUPTURED INTRACRANIAL ANEURYSMS; FLOW DIVERSION; PIPELINE; TRIALS;

D O I：

10.1016/j.wneu.2018.06.127

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Most neurovascular innovations have been introduced by using case series followed by observational studies. A better approach would be a pragmatic randomized trial. Two important aspects of trial design, patient selection and randomized allocation, remain poorly understood. We discuss the role trial methodology can play in the protection of patients being offered innovative treatments.

引用

页码：E99 / E104

页数：6

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