Protecting-group-free amination of halogenated nitrobenzaldehyde with palladium catalyst

被引：4
作者：
Cao, Jing [1 ]
Feng, Jun Xiang [1 ]
Wu, Yong Xiang [1 ]
Tuo, Ya Ya [1 ]
机构：
[1] Xiangtan Univ, Key Lab Environmentally Friendly Chem & Applicat, Minist Educ, Coll Chem, Xiangtan 411105, Peoples R China
来源：
CHINESE CHEMICAL LETTERS | 2010年 / 21卷 / 08期
关键词：
Halogenated nitrobenzaldehyde; Secondary aliphatic amines; Pd catalyst; ARYL HALIDES; DERIVATIVES;
D O I：
10.1016/j.cclet.2010.03.028
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
"One-step" method for the synthesis of secondary aliphatic amine substituted nitrobenzaldehyde was developed. In the presence of Pd catalyst, halogenated nitrobenzaldehyde could be smoothly coupled with secondary aliphatic amine to give the target product in hexamethylphosphamide (HMPT) media without the protection of aldehyde groups. (C) 2010 Jing Cao. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
引用
收藏
页码：935 / 938
页数：4
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