The longitudinal association between lifetime mental disorders and first onset or recurrent suicide ideation

被引:37
作者
de Beurs, Derek [1 ,2 ]
ten Have, Margreet [3 ]
Cuijpers, Pim [2 ]
de Graaf, Ron [3 ]
机构
[1] Netherlands Inst Hlth Serv Res, Utrecht, Netherlands
[2] Vrije Univ Amsterdam, Dept Clin Neuro & Dev Psychol, Amsterdam, Netherlands
[3] Netherlands Inst Mental Hlth & Addict, Utrecht, Netherlands
关键词
Suicidal behavior; Comorbidity; Epidemiology; HEALTH SURVEY; RISK-FACTORS; ANXIETY DISORDERS; POPULATION; BEHAVIORS; PREDICTORS; THOUGHTS; VERSION; ADULT;
D O I
10.1186/s12888-019-2328-8
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
BackgroundAlthough the cross-sectional association between mental disorders and suicide ideation is well studied, less is known about the prospective association. In this paper, we estimated among those without 12-month suicide ideation at baseline, the association between a wide variety of common mental disorders at baseline and suicide ideation within the 6-year follow-up period, after controlling for history of other mental disorders and demographic variables.MethodsData were used from the Netherlands Mental Health Survey and Incidence Study-2 (NEMESIS-2), a prospective representative adult cohort study with baseline (n=6646) with a 6-year follow-up period. Lifetime mental disorders were assessed at baseline with the Composite International Diagnostic Interview 3.0. Within the longitudinal design, participants with first time or recurrent suicide ideation were defined follows: having no suicide ideation in the 12months before the baseline assessment, and reporting to have had seriously thought about suicide between baseline and the 6-year follow-up period. Multiple logistical regression was used to estimate the longitudinal association between suicide ideation and a specific mental disorder while controlling for comorbidity and baseline variables. To account for the prevalence of a disorder in the population, for each disorder, the population attributable risk proportion (PARP) was calculated.Results2.9% (n=132) of the participants that did not report suicide ideation in the past 12months at baseline reported suicide ideation at follow-up. Of these 132 cases, 81 (61%) experienced suicide ideation for the first time in their lives and could be viewed as first onset cases. 51 (39%) reported recurrent suicide ideation. After controlling for comorbidity, the only two disorders that were significantly related to suicide ideation at follow-up were lifetime major depressive disorder (MDD) and generalized anxiety disorder (GAD). PARP for MDD was 47.8 and 16.6% for GAD.ConclusionsAfter controlling for all other mental disorders, a lifetime history of MDD and GAD were related to suicide ideation at follow-up. For clinical practice, this indicates that patients with a history of MDD or GAD stay vulnerable for suicide ideation, even though they did not report suicide ideation in the past year.
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页数:9
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