UV LED arrays at 280 and 340 nm for spectroscopic biosensing

被引:13
作者
Davitt, K.
Song, Y.-K.
Patterson, W.
Nurmikko, A. V. [1 ]
Rer, Z.
Sun, Q.
Han, J.
机构
[1] Brown Univ, Div Engn, Providence, RI 02912 USA
[2] Yale Univ, Dept Elect Engn, New Haven, CT 06520 USA
来源
PHYSICA STATUS SOLIDI A-APPLICATIONS AND MATERIALS SCIENCE | 2007年 / 204卷 / 06期
关键词
D O I
10.1002/pssa.200674925
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
We demonstrate the application of linear arrays of ultraviolet light emitting diodes (UV LEDs) at the wavelengths of 280 nm and 340 nm to the acquisition of fluorescence spectra from single particles in real-time. A compact optical system and custom electronics are employed to produce a compact, standalone biosensor. The detection sensitivity of the UV LED system is established using the biofluorophores tryptophan and NADH, and the capability of the sensor to sort particles based on weak spectra is demonstrated using micron-sized polystyrene latex (PSL) spheres. (C) 2007 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码:2112 / 2116
页数:5
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