Adipose Tissue Composition in Obesity and After Bariatric Surgery

被引：24
作者：
Adami, Gian Franco [1 ,2 ]
Carbone, Federico [1 ,2 ]
Montecucco, Fabrizio [1 ,2 ]
Camerini, Giovanni [1 ,2 ,3 ]
Cordera, Renzo [1 ,2 ]
机构：
[1] Univ Genoa, Dept Internal Med, 8 Viale Benedetto 15, I-16132 Genoa, Italy
[2] Azienda Osped Univ San Martino, IRCCS, Genoa, Italy
[3] Univ Genoa, Dept Surg, Genoa, Italy
来源：
OBESITY SURGERY | 2019年 / 29卷 / 09期
关键词：
Obesity; Epicardial fat; Ectopic fat; Brown adipose tissue; Bariatric surgery; Y GASTRIC BYPASS; FREE FATTY-ACIDS; INSULIN-RESISTANCE; ECTOPIC FAT; EPICARDIAL FAT; LIPID-METABOLISM; MORBID-OBESITY; LIVER-DISEASE; WEIGHT-LOSS; SENSITIVITY;
D O I：
10.1007/s11695-019-04030-z
中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
The adipose tissue is a complex organ that regulates food intake and energy expenditure as well as induces low-grade inflammation. This review deals with changes in the composition and activity of the adipose organ after bariatric surgery, focusing on epicardial and ectopic fat and on relationships between white and brown adipose tissues. Postoperative improvements of ectopic fat and epicardial fat size and composition account for the metabolic recovery and the decreased cardiovascular risk. Following Roux-en-Y gastric bypass or biliopancreatic diversion, a proportional increase in the size and activity of the metabolically active brown adipose tissue was observed, most likely related to the postoperative rearrangement of the entero-hormonal pattern with an increase of GLP-1 production: this aspect would promote the postoperative weight loss and maintenance of post-surgery benefits.
引用
收藏
页码：3030 / 3038
页数：9
相关论文
共 101 条
[81]   Perivascular adipose tissue: An unique fat compartment relevant for the cardiometabolic syndrome [J].
Siegel-Axel, D. I. ;
Haering, H. U. .
REVIEWS IN ENDOCRINE & METABOLIC DISORDERS, 2016, 17 (01) :51-60
[82]   Ectopic fat accumulation in the pancreas and its biomarkers: A systematic review and meta-analysis [J].
Singh, Ruma G. ;
Yoon, Harry D. ;
Poppitt, Sally D. ;
Plank, Lindsay D. ;
Petrov, Maxim S. .
DIABETES-METABOLISM RESEARCH AND REVIEWS, 2017, 33 (08)
[83]   Bariatric surgery and reduction in morbidity and mortality: experiences from the SOS study [J].
Sjostrom, L. .
INTERNATIONAL JOURNAL OF OBESITY, 2008, 32 (Suppl 7) :S93-S97
[84]   Methods for quantifying adipose tissue insulin resistance in overweight/obese humans [J].
ter Horst, K. W. ;
van Galen, K. A. ;
Gilijamse, P. W. ;
Hartstra, A. V. ;
de Groot, P. F. ;
van der Valk, F. M. ;
Ackermans, M. T. ;
Nieuwdorp, M. ;
Romijn, J. A. ;
Serlie, M. J. .
INTERNATIONAL JOURNAL OF OBESITY, 2017, 41 (08) :1288-1294
[85]   Macrophage functions in lean and obese adipose tissue [J].
Thomas, Dylan ;
Apovian, Caroline .
METABOLISM-CLINICAL AND EXPERIMENTAL, 2017, 72 :120-143
[86]   Dose-response relationship between visceral fat index and untreated hypertension in Chinese rural population: the RuralDiab study [J].
Tian, Zhongyan ;
Li, Yuqian ;
Li, Linlin ;
Liu, Xiaotian ;
Shi, Yuanyuan ;
Yang, Kaili ;
Liu, Ruihua ;
Zhang, Honglei ;
Qian, Xinling ;
Yin, Lei ;
Zhao, Jingzhi ;
Wang, Chongjian .
JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION, 2018, 12 (06) :448-456
[87]   Ectopic Fat Accumulation in Distinct Insulin Resistant Phenotypes; Targets for Personalized Nutritional Interventions [J].
Trouwborst, Inez ;
Bowser, Suzanne M. ;
Goossens, Gijs H. ;
Blaak, Ellen E. .
FRONTIERS IN NUTRITION, 2018, 5
[88]   Excess of Free Fatty Acids as a Cause of Metabolic Dysfunction in Skeletal Muscle [J].
Tumova, J. ;
Andel, M. ;
Trnka, J. .
PHYSIOLOGICAL RESEARCH, 2016, 65 (02) :193-207
[89]   Effects of bariatric surgery on pericardial ectopic fat depositions and cardiovascular function [J].
van Schinkel, Linda D. ;
Sleddering, Maria A. ;
Lips, Mirjam A. ;
Jonker, Jacqueline T. ;
de Roos, Albert ;
Lamb, Hildo J. ;
Jazet, Ingrid M. ;
Pijl, Hanno ;
Smit, Johannes W. A. .
CLINICAL ENDOCRINOLOGY, 2014, 81 (05) :689-695
[90]   Increase in Brown Adipose Tissue Activity after Weight Loss in Morbidly Obese Subjects [J].
Vijgen, G. H. E. J. ;
Bouvy, N. D. ;
Teule, G. J. J. ;
Brans, B. ;
Hoeks, J. ;
Schrauwen, P. ;
Lichtenbelt, W. D. van Marken .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2012, 97 (07) :E1229-E1233
234567891011