Adipose Tissue Composition in Obesity and After Bariatric Surgery

被引：24
作者：
Adami, Gian Franco [1 ,2 ]
Carbone, Federico [1 ,2 ]
Montecucco, Fabrizio [1 ,2 ]
Camerini, Giovanni [1 ,2 ,3 ]
Cordera, Renzo [1 ,2 ]
机构：
[1] Univ Genoa, Dept Internal Med, 8 Viale Benedetto 15, I-16132 Genoa, Italy
[2] Azienda Osped Univ San Martino, IRCCS, Genoa, Italy
[3] Univ Genoa, Dept Surg, Genoa, Italy
来源：
OBESITY SURGERY | 2019年 / 29卷 / 09期
关键词：
Obesity; Epicardial fat; Ectopic fat; Brown adipose tissue; Bariatric surgery; Y GASTRIC BYPASS; FREE FATTY-ACIDS; INSULIN-RESISTANCE; ECTOPIC FAT; EPICARDIAL FAT; LIPID-METABOLISM; MORBID-OBESITY; LIVER-DISEASE; WEIGHT-LOSS; SENSITIVITY;
D O I：
10.1007/s11695-019-04030-z
中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
The adipose tissue is a complex organ that regulates food intake and energy expenditure as well as induces low-grade inflammation. This review deals with changes in the composition and activity of the adipose organ after bariatric surgery, focusing on epicardial and ectopic fat and on relationships between white and brown adipose tissues. Postoperative improvements of ectopic fat and epicardial fat size and composition account for the metabolic recovery and the decreased cardiovascular risk. Following Roux-en-Y gastric bypass or biliopancreatic diversion, a proportional increase in the size and activity of the metabolically active brown adipose tissue was observed, most likely related to the postoperative rearrangement of the entero-hormonal pattern with an increase of GLP-1 production: this aspect would promote the postoperative weight loss and maintenance of post-surgery benefits.
引用
收藏
页码：3030 / 3038
页数：9
相关论文
共 101 条
[21]   From the epicardial adipose tissue to vulnerable coronary plaques [J].
Echavarria-Pinto, Mauro ;
Hernando, Lorenzo ;
Alfonso, Fernando .
WORLD JOURNAL OF CARDIOLOGY, 2013, 5 (04) :68-74
[22]   Diet-Induced Obesity and the Mechanism of Leptin Resistance [J].
Engin, Atilla .
OBESITY AND LIPOTOXICITY, 2017, 960 :381-397
[23]   Association of All-Cause Mortality With Overweight and Obesity Using Standard Body Mass Index Categories A Systematic Review and Meta-analysis [J].
Flegal, Katherine M. ;
Kit, Brian K. ;
Orpana, Heather ;
Graubard, Barry I. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2013, 309 (01) :71-82
[24]   Subcutaneous fat thickness, but not epicardial fat thickness, parallels weight reduction three months after bariatric surgery: A cardiac magnetic resonance study [J].
Foppa, Murilo ;
Pond, Kyle K. ;
Jones, Daniel B. ;
Schneider, Benjamin ;
Kissinger, Kraig V. ;
Manning, Warren J. .
INTERNATIONAL JOURNAL OF CARDIOLOGY, 2013, 168 (04) :4532-4533
[25]   Mechanisms of NAFLD development and therapeutic strategies [J].
Friedman, Scott L. ;
Neuschwander-Tetri, Brent A. ;
Rinella, Mary ;
Sanyal, Arun J. .
NATURE MEDICINE, 2018, 24 (07) :908-922
[26]   Ectopic fat storage in the pancreas using 1H-MRS: importance of diabetic status and modulation with bariatric surgery-induced weight loss [J].
Gaborit, B. ;
Abdesselam, I. ;
Kober, F. ;
Jacquier, A. ;
Ronsin, O. ;
Emungania, O. ;
Lesavre, N. ;
Alessi, M-C ;
Martin, J. C. ;
Bernard, M. ;
Dutour, A. .
INTERNATIONAL JOURNAL OF OBESITY, 2015, 39 (03) :480-487
[27]   Role of Epicardial Adipose Tissue in Health and Disease: A Matter of Fat? [J].
Gaborit, Benedicte ;
Sengenes, Coralie ;
Ancel, Patricia ;
Jacquier, Alexis ;
Dutour, Anne .
COMPREHENSIVE PHYSIOLOGY, 2017, 7 (03) :1051-1082
[28]   Effects of Bariatric Surgery on Cardiac Ectopic Fat Lesser Decrease in Epicardial Fat Compared to Visceral Fat Loss and No Change in Myocardial Triglyceride Content [J].
Gaborit, Benedicte ;
Jacquier, Alexis ;
Kober, Frank ;
Abdesselam, Ines ;
Cuisset, Thomas ;
Boullu-Ciocca, Sandrine ;
Emungania, Olivier ;
Alessi, Marie-Christine ;
Clement, Karine ;
Bernard, Monique ;
Dutour, Anne .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2012, 60 (15) :1381-1389
[29]   Intramyocellular lipids and their dynamics assessed by 1H magnetic resonance spectroscopy [J].
Gacesa, J. Popadic ;
Schick, F. ;
Machann, J. ;
Grujic, N. .
CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING, 2017, 37 (06) :558-566
[30]   Pancreatic size and fat content in diabetes: A systematic review and meta-analysis of imaging studies [J].
Garcia, Tiago Severo ;
Rech, Tatiana Helena ;
Leitao, Cristiane Bauermann .
PLOS ONE, 2017, 12 (07)
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