Adipose Tissue Composition in Obesity and After Bariatric Surgery

被引：24
作者：
Adami, Gian Franco [1 ,2 ]
Carbone, Federico [1 ,2 ]
Montecucco, Fabrizio [1 ,2 ]
Camerini, Giovanni [1 ,2 ,3 ]
Cordera, Renzo [1 ,2 ]
机构：
[1] Univ Genoa, Dept Internal Med, 8 Viale Benedetto 15, I-16132 Genoa, Italy
[2] Azienda Osped Univ San Martino, IRCCS, Genoa, Italy
[3] Univ Genoa, Dept Surg, Genoa, Italy
来源：
OBESITY SURGERY | 2019年 / 29卷 / 09期
关键词：
Obesity; Epicardial fat; Ectopic fat; Brown adipose tissue; Bariatric surgery; Y GASTRIC BYPASS; FREE FATTY-ACIDS; INSULIN-RESISTANCE; ECTOPIC FAT; EPICARDIAL FAT; LIPID-METABOLISM; MORBID-OBESITY; LIVER-DISEASE; WEIGHT-LOSS; SENSITIVITY;
D O I：
10.1007/s11695-019-04030-z
中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
The adipose tissue is a complex organ that regulates food intake and energy expenditure as well as induces low-grade inflammation. This review deals with changes in the composition and activity of the adipose organ after bariatric surgery, focusing on epicardial and ectopic fat and on relationships between white and brown adipose tissues. Postoperative improvements of ectopic fat and epicardial fat size and composition account for the metabolic recovery and the decreased cardiovascular risk. Following Roux-en-Y gastric bypass or biliopancreatic diversion, a proportional increase in the size and activity of the metabolically active brown adipose tissue was observed, most likely related to the postoperative rearrangement of the entero-hormonal pattern with an increase of GLP-1 production: this aspect would promote the postoperative weight loss and maintenance of post-surgery benefits.
引用
收藏
页码：3030 / 3038
页数：9
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