Adipose Tissue Composition in Obesity and After Bariatric Surgery

被引：24
作者：
Adami, Gian Franco [1 ,2 ]
Carbone, Federico [1 ,2 ]
Montecucco, Fabrizio [1 ,2 ]
Camerini, Giovanni [1 ,2 ,3 ]
Cordera, Renzo [1 ,2 ]
机构：
[1] Univ Genoa, Dept Internal Med, 8 Viale Benedetto 15, I-16132 Genoa, Italy
[2] Azienda Osped Univ San Martino, IRCCS, Genoa, Italy
[3] Univ Genoa, Dept Surg, Genoa, Italy
来源：
OBESITY SURGERY | 2019年 / 29卷 / 09期
关键词：
Obesity; Epicardial fat; Ectopic fat; Brown adipose tissue; Bariatric surgery; Y GASTRIC BYPASS; FREE FATTY-ACIDS; INSULIN-RESISTANCE; ECTOPIC FAT; EPICARDIAL FAT; LIPID-METABOLISM; MORBID-OBESITY; LIVER-DISEASE; WEIGHT-LOSS; SENSITIVITY;
D O I：
10.1007/s11695-019-04030-z
中图分类号：
R61 [外科手术学];
学科分类号：
摘要：
The adipose tissue is a complex organ that regulates food intake and energy expenditure as well as induces low-grade inflammation. This review deals with changes in the composition and activity of the adipose organ after bariatric surgery, focusing on epicardial and ectopic fat and on relationships between white and brown adipose tissues. Postoperative improvements of ectopic fat and epicardial fat size and composition account for the metabolic recovery and the decreased cardiovascular risk. Following Roux-en-Y gastric bypass or biliopancreatic diversion, a proportional increase in the size and activity of the metabolically active brown adipose tissue was observed, most likely related to the postoperative rearrangement of the entero-hormonal pattern with an increase of GLP-1 production: this aspect would promote the postoperative weight loss and maintenance of post-surgery benefits.
引用
收藏
页码：3030 / 3038
页数：9
相关论文
共 101 条
[1]   Alterations in energy expenditure in Roux-en-Y gastric bypass rats persist at thermoneutrality [J].
Abegg, K. ;
Corteville, C. ;
Bueter, M. ;
Lutz, T. A. .
INTERNATIONAL JOURNAL OF OBESITY, 2016, 40 (08) :1215-1221
[2]   Obesity and diabetes: the link between adipose tissue dysfunction and glucose homeostasis [J].
Abranches, Monise Viana ;
Esteves de Oliveira, Fernanda Cristina ;
da Conceicao, Lisiane Lopes ;
Gouveia Peluzio, Maria do Carmo .
NUTRITION RESEARCH REVIEWS, 2015, 28 (02) :121-132
[3]   Magnetic resonance spectroscopy facilitates assessment of intramyocellular lipid changes: a preliminary short-term study following biliopancreatic diversion [J].
Adami, GF ;
Parodi, RC ;
Papadia, F ;
Marinari, G ;
Camerini, G ;
Corvisieri, R ;
Scopinaro, N .
OBESITY SURGERY, 2005, 15 (09) :1233-1237
[4]   Long-term mortality after gastric bypass surgery [J].
Adams, Ted D. ;
Gress, Richard E. ;
Smith, Sherman C. ;
Halverson, R. Chad ;
Simper, Steven C. ;
Rosamond, Wayne D. ;
LaMonte, Michael J. ;
Stroup, Antoinette M. ;
Hunt, Steven C. .
NEW ENGLAND JOURNAL OF MEDICINE, 2007, 357 (08) :753-761
[5]   Loss of Antigen Presentation in Adipose Tissue Macrophages or in Adipocytes, but Not Both, Improves Glucose Metabolism [J].
Blaszczak, Alecia M. ;
Wright, Valerie P. ;
Anandani, Kajol ;
Liu, Joey ;
Jalilvand, Anahita ;
Bergin, Stephen ;
Nicoloro, Sarah M. ;
Czech, Michael P. ;
Lafuse, William ;
Deng, Tuo ;
Bradley, David ;
Hsueh, Willa A. .
JOURNAL OF IMMUNOLOGY, 2019, 202 (08) :2451-2459
[6]   Bariatric surgery: A systematic review and meta-analysis [J].
Buchwald, H ;
Avidor, Y ;
Braunwald, E ;
Jensen, MD ;
Pories, W ;
Fahrbach, K ;
Schoelles, K .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2004, 292 (14) :1724-1737
[7]   Contribution of Adipose Tissue Inflammation to the Development of Type 2 Diabetes Mellitus [J].
Burhans, Maggie S. ;
Hagman, Derek K. ;
Kuzma, Jessica N. ;
Schmidt, Kelsey A. ;
Kratz, Mario .
COMPREHENSIVE PHYSIOLOGY, 2019, 9 (01) :1-58
[8]   Muscle and adipose tissue morphology, insulin sensitivity and beta-cell function in diabetic and nondiabetic obese patients: effects of bariatric surgery [J].
Camastra, Stefania ;
Vitali, Alessandra ;
Anselmino, Marco ;
Gastaldelli, Amalia ;
Bellini, Rosario ;
Berta, Rossana ;
Severi, Ilenia ;
Baldi, Simona ;
Astiarraga, Brenno ;
Barbatelli, Giorgio ;
Cinti, Saverio ;
Ferrannini, Ele .
SCIENTIFIC REPORTS, 2017, 7
[9]   Pharmacology, Physiology, and Mechanisms of Incretin Hormone Action [J].
Campbell, Jonathan E. ;
Drucker, Daniel J. .
CELL METABOLISM, 2013, 17 (06) :819-837
[10]   Short- and long-term mortality after bariatric surgery: A systematic review and meta-analysis [J].
Cardoso, Luis ;
Rodrigues, Dircea ;
Gomes, Leonor ;
Carrilho, Francisco .
DIABETES OBESITY & METABOLISM, 2017, 19 (09) :1223-1232
12345678910