High-sensitivity cardiac troponin assays and acute coronary syndrome: a matter of sex?

被引:18
作者
Rocco, Erica [1 ,2 ]
La Rosa, Giulio [1 ,2 ]
Liuzzo, Giovanna [1 ,2 ]
Biasucci, Luigi M. [1 ,2 ]
机构
[1] Univ Cattolica Sacro Cuore, Dept Cardiovasc & Thorac Sci, Rome, Italy
[2] Fdn Policlin Univ A Gemelli IRCCS, Rome, Italy
关键词
acute coronary syndromes; cardiac troponin; sex; MYOCARDIAL-INFARCTION; PROGNOSTIC VALUE; EARLY-DIAGNOSIS; I ASSAY; REFERENCE LIMITS; HEART-DISEASE; UNITED-STATES; GENDER; RISK; MORTALITY;
D O I
10.2459/JCM.0000000000000811
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Advances in technology have led to an improvement in the ability to detect and quantify acute cardiomyocyte injury with the measurement of high-sensitivity cardiac troponin as compared with conventional assays. The upper reference limit for the high-sensitivity cardiac troponin assays is defined as the 99th percentile cutoff value in a healthy reference population. Since sex-related threshold levels of high-sensitivity cardiac troponin assays have been proposed, this review will focus on the diagnostic and prognostic implications of adopting sex-specific threshold troponin values in patients with a suspected acute coronary syndrome.
引用
收藏
页码:504 / 509
页数:6
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