High-sensitivity cardiac troponin assays and acute coronary syndrome: a matter of sex?

被引:18
作者
Rocco, Erica [1 ,2 ]
La Rosa, Giulio [1 ,2 ]
Liuzzo, Giovanna [1 ,2 ]
Biasucci, Luigi M. [1 ,2 ]
机构
[1] Univ Cattolica Sacro Cuore, Dept Cardiovasc & Thorac Sci, Rome, Italy
[2] Fdn Policlin Univ A Gemelli IRCCS, Rome, Italy
关键词
acute coronary syndromes; cardiac troponin; sex; MYOCARDIAL-INFARCTION; PROGNOSTIC VALUE; EARLY-DIAGNOSIS; I ASSAY; REFERENCE LIMITS; HEART-DISEASE; UNITED-STATES; GENDER; RISK; MORTALITY;
D O I
10.2459/JCM.0000000000000811
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Advances in technology have led to an improvement in the ability to detect and quantify acute cardiomyocyte injury with the measurement of high-sensitivity cardiac troponin as compared with conventional assays. The upper reference limit for the high-sensitivity cardiac troponin assays is defined as the 99th percentile cutoff value in a healthy reference population. Since sex-related threshold levels of high-sensitivity cardiac troponin assays have been proposed, this review will focus on the diagnostic and prognostic implications of adopting sex-specific threshold troponin values in patients with a suspected acute coronary syndrome.
引用
收藏
页码:504 / 509
页数:6
相关论文
共 61 条
[1]   Troponin elevation in coronary vs. non-coronary disease [J].
Agewall, S. ;
Giannitsis, E. ;
Jernberg, T. ;
Katus, H. .
EUROPEAN HEART JOURNAL, 2011, 32 (04) :404-411B
[2]  
[Anonymous], COMPR MORT FIL UND C
[3]   Decision making with cardiac troponin tests [J].
Antman, EM .
NEW ENGLAND JOURNAL OF MEDICINE, 2002, 346 (26) :2079-2082
[4]   Men are different than women: It's true for cardiac troponin too [J].
Apple, Fred S. ;
Jaffe, Allan S. .
CLINICAL BIOCHEMISTRY, 2014, 47 (10-11) :867-868
[5]   Determination of 19 Cardiac Troponin I and T Assay 99th Percentile Values from a Common Presumably Healthy Population [J].
Apple, Fred S. ;
Ler, Ranka ;
Murakami, MaryAnn M. .
CLINICAL CHEMISTRY, 2012, 58 (11) :1574-1581
[6]   Analytical Characteristics of High-Sensitivity Cardiac Troponin Assays [J].
Apple, Fred S. ;
Collinson, Paul O. .
CLINICAL CHEMISTRY, 2012, 58 (01) :54-61
[7]   Plasma 99th percentile reference limits for cardiac troponin and creatine kinase MB mass for use with European Society of Cardiology American College of Cardiology consensus recommendations [J].
Apple, FS ;
Quist, HE ;
Doyle, PJ ;
Otto, AP ;
Murakami, MM .
CLINICAL CHEMISTRY, 2003, 49 (08) :1331-1336
[8]   Quality specifications for B-type natriuretic peptide assays [J].
Apple, FS ;
Panteghini, M ;
Ravkilde, J ;
Mair, J ;
Wu, AHB ;
Tate, J ;
Pagani, F ;
Christenson, RH ;
Jaffe, AS .
CLINICAL CHEMISTRY, 2005, 51 (03) :486-493
[9]   Chest pain and shortness of breath in cardiovascular disease: a prospective cohort study in UK primary care [J].
Barnett, Lauren A. ;
Prior, James A. ;
Kadam, Umesh T. ;
Jordan, Kelvin P. .
BMJ OPEN, 2017, 7 (05)
[10]   Association of Troponin T Detected With a Highly Sensitive Assay and Cardiac Structure and Mortality Risk in the General Population [J].
de Lemos, James A. ;
Drazner, Mark H. ;
Omland, Torbjorn ;
Ayers, Colby R. ;
Khera, Amit ;
Rohatgi, Anand ;
Hashim, Ibrahim ;
Berry, Jarett D. ;
Das, Sandeep R. ;
Morrow, David A. ;
McGuire, Darren K. .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2010, 304 (22) :2503-2512