Histologic evidence of tracheal stenosis directly resulting from SARS-CoV-2 tissue infiltration, a case series

被引：6

作者：

Draeger, Tyler B. ^{[1
]}

Tedesco, Sarah ^{[2
]}

Andaz, Shahriyour K. ^{[3
]}

Gibson, Vanessa R. ^{[3
]}

机构：

[1] Icahn Sch Med Mt Sinai, Mt Sinai South Nassau, Dept Surg, Oceanside, NY USA

[2] Amer Univ, Antigua Coll Med, Collidge, Antigua & Barbu

[3] Icahn Sch Med Mt Sinai, Mt Sinai South Nassau, Dept Surg, Div Cardiothorac Surg, 1 Hlth Way, Oceanside, NY 11572 USA

来源：

JOURNAL OF CARDIOTHORACIC SURGERY | 2022年 / 17卷 / 01期

关键词：

Tracheal stenosis; Thoracic surgery; SARS-CoV-2; Tracheal resection; Dilatation; Case series;

D O I：

10.1186/s13019-022-01839-1

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background There has been an anecdotal increase in the incidence of tracheal stenosis that has coincided with the SARS-CoV-2 pandemic. Case presentation This is a case series in which we report clinical and pathologic findings of two patients who subsequently developed subglottic tracheal stenosis after having been hospitalized with COVID-19 pneumonia. Histopathologic analysis of tissue from these patients shows features consistent with tissue infiltrated with SARS-CoV-2 virus, namely multinucleated syncytial cells with prominent nucleoli. Conclusion Our findings directly implicate SARS-CoV-2 in the pathogenesis of tracheal stenosis.

引用

页数：5

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