Modulating Cholesterol Homeostasis to Build a Better T Cell

被引：32

作者：

Kidani, Yoko ^{[1
]}

Bensinger, Steven J. ^{[1
,2
]}

机构：

[1] Univ Calif Los Angeles, David Geffen Sch Med, Dept Microbiol Immunol & Mol Genet, Los Angeles, CA 90095 USA

[2] Univ Calif Los Angeles, David Geffen Sch Med, Dept Mol & Med Pharmacol, Los Angeles, CA 90095 USA

来源：

CELL METABOLISM | 2016年 / 23卷 / 06期

关键词：

METABOLISM;

D O I：

10.1016/j.cmet.2016.05.015

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

There is great interest in discovering targets for in vitro manipulation of autologous T cells that enhance their cytotoxicity against tumor targets as a potent cancer immunotherapy. In a recent Nature paper, Xu and colleagues reveal new insights into the link between cellular cholesterol metabolism and CD8 T cell functions.

引用

收藏

页码：963 / 964

页数：2

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