Transient heart block in a neonate associated with previously undiagnosed maternal anti-Ro/SSA and anti-La/SSB antibodies

被引:2
|
作者
Escamilla, S. A.
Pettersen, M. D.
机构
[1] Wayne State Univ, Sch Med, Carmen & Ann Adams Dept Pediat, Detroit, MI 48201 USA
[2] Childrens Hosp Michigan, Detroit, MI 48201 USA
关键词
transient congenital heart block; anti-SSA/Ro antibodies; Anti-SSB/La antibodies; ENDOCARDIAL FIBROELASTOSIS; QT INTERVAL; SSA/RO; RO; AUTOANTIBODIES; MOTHERS;
D O I
10.1007/s00246-006-0015-2
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
This report presents the case of an infant who was born with transient complete heart block. The cardiac rhythm converted to normal sinus rhythm within 12 hours of life. Following the diagnosis in this infant of congenital heart block, both the mother and the infant were tested for autoantibodies. Both were found to be strongly positive for anti-Ro/SSA antibodies. The infant was also weakly positive for the anti-La/SSB antibodies and her mother moderately positive for the same. Congenital heart block associated with these maternal antibodies is well documented in the literature; however, this is the only reported case that documents a transient nature of the complete heart block.
引用
收藏
页码:221 / 223
页数:3
相关论文
共 50 条
  • [31] Atrioventricular Conduction Delay in Fetuses Exposed to Anti-SSA/Ro and Anti-SSB/La Antibodies: A Magnetocardiography Study
    Wacker-Gussmann, Annette
    Paulsen, Henrike
    Kiefer-Schmidt, Isabelle
    Henes, Joerg
    Muenssinger, Jana
    Weiss, Magdalene
    Goelz, Rangmar
    Preissl, Hubert
    CLINICAL & DEVELOPMENTAL IMMUNOLOGY, 2012,
  • [32] Early Diagnosis and Treatment of Atrioventricular Block in the Fetus Exposed to Maternal Anti-SSA/Ro-SSB/La Antibodies A Prospective, Observational, Fetal Kinetocardiogram-Based Study
    Rein, A. J. J. T.
    Mevorach, D.
    Perles, Z.
    Gavri, S.
    Nadjari, M.
    Nir, A.
    Elchalal, U.
    CIRCULATION, 2009, 119 (14) : 1867 - 1872
  • [33] Outcome in 212 anti-Ro/SSA-positive pregnancies and population-based incidence of congenital heart block
    Skog, Amanda
    Lagnefeldt, Linda
    Conner, Peter
    Wahren-Herlenius, Marie
    Sonesson, Sven-Erik
    ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA, 2016, 95 (01) : 98 - 105
  • [34] Anti-Ro and anti-La seropositivity is associated with increased rates of ischemic heart disease in adults: Results from a large population-based study
    Ben-Shabat, Niv
    Krasun, Anna
    Fisher, Lior
    Patt, Yonatan Shneor
    Strosberg, Ilana Balassiano
    Watad, Abdulla
    Beinart, Roy
    Cohen, Arnon D.
    Amital, Howard
    ATHEROSCLEROSIS, 2024, 396
  • [35] Anti-Ro/SSA antibodies and cardiac rhythm disturbances: Present and future perspectives
    Santos-Pardo, Irene
    Villuendas, Roger
    Salvador-Corres, Inaki
    Martinez-Morillo, Melania
    Olive, Alejandro
    Bayes-Genis, Antoni
    INTERNATIONAL JOURNAL OF CARDIOLOGY, 2015, 184 : 244 - 250
  • [36] Passively Acquired Anti-SSA/Ro Antibodies Are Required for Congenital Heart Block Following Ovodonation but Maternal Genes Are Not
    Brucato, Antonio
    Ramoni, Veronique
    Penco, Silvana
    Sala, Elena
    Buyon, Jill
    Clancy, Robert
    ARTHRITIS AND RHEUMATISM, 2010, 62 (10): : 3119 - 3121
  • [37] Modulation of the Fcγ receptors induced by anti-Ro and anti-La autoantibodies:: observations in salivary gland cells
    Lisi, Sabrina
    D'Amore, Massimo
    Lofrumento, Dario
    Mitolo, Vincenzo
    Frassanito, Maria Antonia
    Dammacco, Francesco
    Scagliusi, Pasquale
    Sisto, Margherita
    RHEUMATOLOGY INTERNATIONAL, 2008, 28 (09) : 943 - 948
  • [38] Modulation of the Fcγ receptors induced by anti-Ro and anti-La autoantibodies: observations in salivary gland cells
    Sabrina Lisi
    Massimo D’Amore
    Dario Lofrumento
    Vincenzo Mitolo
    Maria Antonia Frassanito
    Francesco Dammacco
    Pasquale Scagliusi
    Margherita Sisto
    Rheumatology International, 2008, 28 : 943 - 948
  • [39] Low titer, isolated anti Ro/SSA 60 kd antibodies is correlated with positive pregnancy outcomes in women at risk of congenital heart block
    Tonello, Marta
    Hoxha, Ariela
    Mattia, Elena
    Zambon, Alessandra
    Visentin, Silvia
    Cerutti, Alessia
    Ghirardello, Anna
    Milanesi, Ornella
    Ruffatti, Amelia
    CLINICAL RHEUMATOLOGY, 2017, 36 (05) : 1155 - 1160
  • [40] DETECTION OF ANTI-RO(SSA) ANTIBODIES IN AUTOIMMUNE-DISEASES - COMPARISON OF 5 METHODS
    MANOUSSAKIS, MN
    KISTIS, KG
    LIU, X
    AIDINIS, V
    GUIALIS, A
    MOUTSOPOULOS, HM
    BRITISH JOURNAL OF RHEUMATOLOGY, 1993, 32 (06): : 449 - 455