Succession of oral microbiota community as a tool to estimate postmortem interval

被引：36

作者：

Dong, Kaikai ^{[1
]}

Xin, Ye ^{[1
]}

Cao, Fangqi ^{[1
,2
]}

Huang, Zhiwei ^{[3
]}

Sun, Jing ^{[4
]}

Peng, Min ^{[4
]}

Liu, Wenbin ^{[2
]}

Shi, Ping ^{[1
,4
]}

机构：

[1] East China Univ Sci & Technol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China

[2] Shanghai Res Inst Criminal Sci & Technol, Shanghai Key Lab Crime Scene Evidence, Zhongshan North 1 Rd, Shanghai 200083, Peoples R China

[3] Donghua Univ, Key Lab Sci & Technol Ecotext, Minist Educ, Coll Chem Chem Engn & Biotechnol, 2999 Renmin Rd, Shanghai 201620, Peoples R China

[4] Chinese Acad Sci, Qinghai Key Lab Qinghai Tibet Plateau Biol Resour, Northwest Inst Plateau Biol, Xiguan Ave 59, Xining 810001 11, Qinghai, Peoples R China

来源：

SCIENTIFIC REPORTS | 2019年 / 9卷 / 1期

基金：

中国国家自然科学基金;

关键词：

TIME; TEMPERATURE; SEQUENCES; DIVERSITY;

D O I：

10.1038/s41598-019-49338-z

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The establishment of postmortem interval is one of the most important aspects of forensic expertise. Microbes may provide a novel way to estimate the postmortem intervals in order to avoid many of these limitations. The oral cavity harbors one of the most diverse microbiomes that play a key role in the decomposition of corpses. In this study, the oral bacterial community showed obvious changes in relative abundance during the process of mice decomposition. Meanwhile, at different taxonomic levels, specific bacteria were found to be significantly correlated with the postmortem interval. Linear regression models between relative abundance and the postmortem interval were constructed. Among these species, Gamma-proteobacteria and Proteus were the best ones that can be used to infer the postmortem interval, especially late postmortem interval. Therefore, we suggest that succession of oral microbial community can be developed as a forensic tool for estimating the postmortem interval.

引用

页数：9

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