Assessment of C-Reactive Protein Level in Oral Submucous Fibrosis and Oral Squamous Cell Carcinoma Patient

被引:0
作者
Sharma, Geeta [1 ]
Kumar, Randhir [2 ]
Salam, Sharib Abdus [2 ]
Bhasin, Prashant [3 ]
Tewari, Nishant Kumar [4 ]
Yadav, Suman [5 ]
机构
[1] Sarjug Dent Coll, Dept Oral Pathol, Darbhanga, Bihar, India
[2] Patna Dent Coll & Hosp, Dept Periodont & Oral Implantol, Patna, Bihar, India
[3] Shree Bankey Bihari Dent Coll, Dept Conservat Dent & Endodont, Ghaziabad, Uttar Pradesh, India
[4] Nalanda Med Coll & Hosp, Deixtrtmait Dent, Patna, Bihar, India
[5] ITS Dent Coll, Dept Oral & Maxillofacial Surg, Ghaziabad, Uttar Pradesh, India
关键词
C-reactive protein; immunoturbidimetry; oral squamous cell carcinoma; oral submucous fibrosis; CANCER; SERUM;
D O I
10.4103/jpbs.JPBS_607_20
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Background: Potentially malignant disorders are highly prevalent in India. In this study, we assessed C-reactive protein (CRP) levels in patients with oral submucous fibrosis (OSMF) and oral squamous cell carcinoma (OSCC). Methodology: Sixty-four patients (OSMF and OSCC) were undertaken and were classified into 3 groups, OSMF patients (Group I, 34), OSCC (Group II, 30), and healthy controls (Group III, 26). Immunoturbidimetry method was used for the estimation of CRP levels. Results: Maximum cases in Group I was seen in the age group 40-60 years (males-10, females-3), Group II in the age group 40-60 years (males-11, females-5) and Group III (males-5, females-6). The mean CRP level in Group I was 6.12 +/- 4.5 mg/l, in Group II was 28.4 +/- 21.5 mg/l, and in Group III was 3.15 +/- 2.19 mg/l. The difference was significant (P < 0.05). Conclusion: Authors found that OSMF and oral cancer patients had increased CRP levels as compared to healthy subjects.
引用
收藏
页码:748 / 750
页数:3
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