Renin-angiotensin-aldosterone system in pregnancy-induced hypertension

被引：10

作者：

Israel, A ^{[1
]}

Peceño, A ^{[1
]}

机构：

[1] Cent Univ Venezuela, Sch Pharm, Caracas, Venezuela

来源：

JOURNAL OF HUMAN HYPERTENSION | 2000年 / 14卷 / Suppl 1期

关键词：

plasma angiotensin-converting enzyme; normotensive pregnant women; pregnancy-induced hypertension; preeclampsia;

D O I：

10.1038/sj.jhh.1000985

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

Angiotensin-converting enzyme (ACE) and aldosterone concentration were measured in the plasma of 32 pregnant women with normal blood pressure or with pregnancy-induced hypertension (PIH). Mean arterial pressure (MAP) in PIH women was significantly higher than in normotensive pregnant women. Plasma ACE activity and aldosterone concentration in 17 PIH patients was significantly lower than their normotensive counterparts (15 cases). Mean arterial pressure was negatively correlated with the level of plasma ACE activity and with plasma aldosterone concentration in all pregnant women. Our results indicate that the circulating renin-angiotensin-aldosterone system is suppressed in pregnancy-induced hypertension.

引用

页码：S36 / S39

页数：4

共 17 条

[1]

Crutchley D J, 1983, Adv Exp Med Biol, V156, P527

[2] SERUM ANGIOTENSIN-CONVERTING ENZYME-ACTIVITY IN PREECLAMPTIC PREGNANCY - EVIDENCE FOR A RELATIVE HYPERMESOR ACEMIA [J].