Basiliximab interferes with the detection of soluble IL-2 receptor by the Immulite Immunoassay system

被引：7
作者：
Warlé, MC
Kwekkeboom, J
Tilanus, HW
Metselaar, HJ
机构：
[1] Erasmus MC, Dept Gastroenterol & Hepatol, NL-3000 CA Rotterdam, Netherlands
[2] Erasmus MC, Dept Surg, NL-3000 CA Rotterdam, Netherlands
来源：
JOURNAL OF IMMUNOLOGICAL METHODS | 2003年 / 275卷 / 1-2期
关键词：
soluble IL-2 receptor; Immulite Immunoassay System; basiliximab;
D O I：
10.1016/S0022-1759(03)00016-4
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
The use of the Immulite Automated Immunoassay system is becoming an increasingly popular method for accurate and fast measurement of sIL-2R in serum. Here, we report that detection of sIL-2R using the Immulite Immunoassay system in serum samples of patients who are treated with basiliximab, a monoclonal antibody against the alpha-chain of the IL-2 receptor, may lead to false measurements. (C) 2003 Elsevier Science B.V. All rights reserved.
引用
收藏
页码：133 / 136
页数：4
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