Antimycobacterial activity of lichens

被引：20

作者：

Gupta, Vivek Kumar ^{[1
]}

Darokar, Mahendra P. ^{[1
]}

Saikia, Dharmendra ^{[1
]}

Pal, Anirban ^{[1
]}

Fatima, Atiya ^{[1
]}

Khanuja, Suman P. S. ^{[1
]}

机构：

[1] CSIR, Cent Inst Med & Aromat Plants, Lucknow 226015, Uttar Pradesh, India

来源：

PHARMACEUTICAL BIOLOGY | 2007年 / 45卷 / 03期

关键词：

antimycobacterial agents; BACTEC; lichens; Mycobacterium tuberculosis; radiometric assay;

D O I：

10.1080/13880200701213088

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Ethanol extracts of nine lichen species, namely Everniastrum cirrhatum ( Fr.) Hale ex Sipman ( Parmeliaceae), Flavoparmelia caperata ( L) Hale ( Parmeliaceae), Heterodermia leucomela ( L) Poelt ( Physciaceae), Lecanora flavidorufa Hue ( Lecanoraceae), Leptogium pedicellatum P. M. Jorg ( Collemataceae), Lobaria isidiosa ( Bory) Trevisan ( Stictaceae), Rimelia reticulata ( Taylor) Hale and Fletcher ( Parmeliaceae), Phaeophyscia hispidula ( Ach.) Essl ( Physciaceae), and Stereocaulon foliolosum Nyl. ( Stereocaulaceae), were evaluated for antimycobacteral properties against Mycobacterium tuberculosis H(37)Rv and H37Ra strains using the radiometric BACTEC method. Among the tested lichens, the virulent strain of M. tuberculosis H37Rv was found more susceptible to ethanol extract of F. caperata and H. leucomela( MIC 250 mu g/mL). E. cirrhatum, R. reticulata, and S. foliolosum were found active at the concentration of 500 mu g/mL. L. isidiosa, L. pedicellatum, P. hispidula, and L. flavidorufa did not exhibit activity at the maximum tested concentration of 1000 mu g/mL.

引用

页码：200 / 204

页数：5

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