A highly fluorescent turn-on probe in the near-infrared region for albumin quantification in serum matrix

被引:73
作者
Chakraborty, Goutam [1 ,2 ]
Ray, Alok K. [1 ,2 ]
Singh, Prabhat K. [2 ,3 ]
Pal, Haridas [2 ,3 ]
机构
[1] Bhabha Atom Res Ctr, Laser & Plasma Technol Div, Bombay 400085, Maharashtra, India
[2] Homi Bhabha Natl Inst, Training Sch Complex, Bombay 400094, Maharashtra, India
[3] Bhabha Atom Res Ctr, Radiat & Photochem Div, Bombay 400085, Maharashtra, India
关键词
OPTICAL-PROPERTIES; RENAL-DISEASE; LDS; 798; SENSOR; DYE; BINDING; MICROALBUMINURIA; NANOPARTICLES; MODULATION; RED;
D O I
10.1039/c8cc05058a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Developing sensitive and selective near-infrared fluorescent bioprobes for serum albumin detection is an ambitious and highly rewarding task. Herein, we report a styryl based fluorophore for serum albumin detection, which displays an exceptional turn-on emission enhancement of B500 fold, the highest reported so far in the near-infrared region, and more importantly enables quantification of albumin in the complex serum matrix.
引用
收藏
页码:8383 / 8386
页数:4
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