Cascade photocaging of diazeniumdiolate: a novel strategy for one and two photon triggered uncaging with real time reporting

被引：25

作者：

Behara, Krishna Kalyani ^{[1
]}

Rajesh, Y. ^{[2
]}

Venkatesh, Yarra ^{[1
]}

Pinninti, Bhaskar Rao ^{[1
]}

Mandal, Mahitosh ^{[2
]}

Singh, N. D. Pradeep ^{[1
]}

机构：

[1] Indian Inst Technol Kharagpur, Dept Chem, Kharagpur 721302, W Bengal, India

[2] Indian Inst Technol IIT Kharagpur, Sch Med Sci & Technol, Kharagpur 721302, W Bengal, India

来源：

CHEMICAL COMMUNICATIONS | 2017年 / 53卷 / 68期

关键词：

CONTROLLED PHOTOCHEMICAL RELEASE; NITRIC-OXIDE; PROTECTING GROUPS; EXCITATION; SYSTEMS; PRODRUG;

D O I：

10.1039/c7cc04635a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report a new strategy, viz. cascade photocaging, for protecting diethylamine diazeniumdiolate (O-2-position), a light sensitive molecule. Upon photolysis, the cascade photocage at first releases the light activatable linker (latent fluorophore) O-2-caged diazeniumdiolate, which undergoes spontaneous 1,8-elimination, triggering the release of the diazeniumdiolate anion and the fluorophore.

引用

页码：9470 / 9473

页数：4

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