Irreversible long-term pulmonary functional impairments after adenovirus type-7 pneumonia: assessment with xenon-133 ventilation and Tc-99-m MAA perfusion studies

A 3-year-old child presented with severe type-7 adenoviral pneumonia. after the resolution of fuse pulmonary infiltrates of the pneumonia. Xenon-133 ventilation and Tc-99-m macroaggregated albumin (MAA) perfusion studies revealed a localized airflow obstruction and matched perfusion defect, and marked air trapping in the remaining lungs, and these abnormalities were not detected and not suspected even with CT. Therefore, in a relatively short period, the child developed persistent bronchiectatic ges and pulmonary hyperinflation throughout the lungs. However, the scintigraphic findings were not significantly changed. This is the first description radionuclide scintigraphic findings which clearly showed an in eversible long-term functional effect of adenoviral pneumonia.