Biomimetic Syntheses of the Neurotrophic Natural Products Caryolanemagnolol and Clovanemagnolol

被引：36

作者：

Cheng, Xu ^{[1
]}

Harzdorf, Nicole L. ^{[1
]}

Shaw, Travis ^{[1
]}

Siegel, Dionicio ^{[1
]}

机构：

[1] Univ Texas Austin, Dept Chem & Biochem, Austin, TX 78712 USA

来源：

ORGANIC LETTERS | 2010年 / 12卷 / 06期

关键词：

MAGNOLIA-OBOVATA THUNB; SINDORA-SUMATRANA MIQ; KINETIC RESOLUTION; COUPLING REACTIONS; JUVENILE-HORMONE; DRIED PODS; CONSTITUENTS; EPOXIDATION; COMPONENTS; EPOXIDES;

D O I：

10.1021/ol100214x

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Separate short and modular syntheses of the isomeric natural products caryolanemagnolol and clovanemagnolol have been achieved starting from commercially available (-)-caryophyllene. The postulated biosynthetic pathways guided the syntheses of the neuro regenerative small molecules allowing their assembly in as few as two steps.

引用

页码：1304 / 1307

页数：4