FruR mediates catabolite activation of pyruvate kinase (pykF) gene expression in Escherichia coli

被引:47
作者
Bledig, SA
Ramseier, TM
Saier, MH
机构
[1] UNIV CALIF SAN DIEGO, DEPT BIOL, LA JOLLA, CA 92093 USA
[2] NSC TECHNOL, MT PROSPECT, IL 60056 USA
关键词
D O I
10.1128/jb.178.1.280-283.1996
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Expression of a pykF-lacZ fusion was studied as a function of the carbon source in wild-type strains and strains lacking or overproducing the FruR protein of Escherichia coli, FruR controls the response to the carbon source by repressing pykF expression more strongly under gluconeogenic than under glycolytic conditions, a phenomenon rye term catabolite activation.
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页码:280 / 283
页数:4
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