Synthesis of Isoquinolines from Benzimidates and Alkynes via Cobalt(III)-Catalyzed C-H Functionalization/Cyclization

被引：29

作者：

Gong, Shasha ^{[1
]}

Xi, Wanlin ^{[1
]}

Ding, Zhenhua ^{[1
]}

Sun, Haiying ^{[1
]}

机构：

[1] China Pharmaceut Univ, Dept Med Chem, Jiangsu Key Lab Drug Design & Optimizat, Nanjing 210009, Jiangsu, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2017年 / 82卷 / 14期

基金：

中国国家自然科学基金;

关键词：

BOND ACTIVATION; BENZODIAZEPINE-RECEPTOR; DIAZO-COMPOUNDS; 4+2 ANNULATION; N-OXIDES; ACCESS; CATALYSIS; OXIMES; AMINES; ARENES;

D O I：

10.1021/acs.joc.7b01052

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

C-1-I alkenylation/annulation of benzimidates with alkynes has been realized by using a Cp*Co(III) catalyst under air. A series of substituted isoquinolines were obtained with moderate to good yields under mild reaction conditions.

引用

页码：7643 / 7647

页数：5

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