The neural correlates of cognitive behavioral therapy: Recent progress in the investigation of patients with panic disorder

被引：19
作者：
Yang, Yunbo [1 ]
Kircher, Tilo [1 ]
Straube, Benjamin [1 ]
机构：
[1] Univ Marburg, Dept Psychiat & Psychotherapy, Rudolf Bultmann Str 8, D-35039 Marburg, Germany
来源：
BEHAVIOUR RESEARCH AND THERAPY | 2014年 / 62卷
关键词：
Exposure-based cognitive behavior therapy; Panic disorder with agoraphobia; fMRI; Neural correlates; Mechanism of action; Outcome prediction; Moderator; RANDOMIZED CONTROLLED-TRIAL; ANXIETY DISORDERS; MONOAMINE-OXIDASE; PREFRONTAL CORTEX; MULTICENTER FMRI; CONDITIONED FEAR; GUIDED EXPOSURE; GENE PROMOTER; PSYCHOTHERAPY; EXTINCTION;
D O I：
10.1016/j.brat.2014.07.011
中图分类号：
B849 [应用心理学];
学科分类号：
040203 ;
摘要：
Cognitive behavioral therapy (CBT) is an evidence-based treatment for mental disorders. Several meta-analytical reviews supported its efficacy and effectiveness in the treatment of panic disorder with agoraphobia (PD/AG). Recently, it has been shown that neurobiological changes are associated with the process and outcome of CBT. However, the general and specific neurobiological effects of CBT are still widely unknown. Therefore, the potential of applying neuroscience to clinical practice and optimizing CBT is still limited. The current review summarizes recent findings about the neural correlates of CBT in PD/AG measured with fMRI. Furthermore, the current review will focus on neural activation patterns predicting and moderating therapeutic success of CBT, due to its potential application in personalized treatment in the future. Finally, we will discuss some future perspectives of the neurosciences in CBT research. (C) 2014 Elsevier Ltd. All rights reserved.
引用
收藏
页码：88 / 96
页数：9
相关论文
共 72 条
  • [1] [Anonymous], 2000, DIAGN STAT MAN MENT, DOI DOI 10.1176/APPI.BOOKS.9780890425787
  • [2] Single-Subject Anxiety Treatment Outcome Prediction using Functional Neuroimaging
    Ball, Tali M.
    Stein, Murray B.
    Ramsawh, Holly J.
    Campbell-Sills, Laura
    Paulus, Martin P.
    [J]. NEUROPSYCHOPHARMACOLOGY, 2014, 39 (05) : 1254 - 1261
  • [3] The effects of psychotherapy on brain function: A systematic and critical review
    Barsaglini, Alessio
    Sartori, Giuseppe
    Benetti, Stefania
    Pettersson-Yeo, William
    Mechelli, Andrea
    [J]. PROGRESS IN NEUROBIOLOGY, 2014, 114 : 1 - 14
  • [4] Cognitive Therapy: Current Status and Future Directions
    Beck, Aaron T.
    Dozois, David J. A.
    [J]. ANNUAL REVIEW OF MEDICINE, VOL 62, 2011, 2011, 62 : 397 - 409
  • [5] Therapygenetics: moving towards personalized psychotherapy treatment
    Beevers, Christopher G.
    McGeary, John E.
    [J]. TRENDS IN COGNITIVE SCIENCES, 2012, 16 (01) : 11 - 12
  • [6] Changes of brain activation pre- post short-term psychodynamic inpatient psychotherapy: An fMRI study of panic disorder patients
    Beutel, Manfred E.
    Stark, Rudolf
    Pan, Hong
    Silbersweig, David
    Dietrich, Sylvia
    [J]. PSYCHIATRY RESEARCH-NEUROIMAGING, 2010, 184 (02) : 96 - 104
  • [7] Neural mechanisms underlying selective attention to threat
    Bishop, Sonia J.
    [J]. MOLECULAR AND BIOPHYSICAL MECHANISMS OF AROUSAL, ALERTNESS, AND ATTENTION, 2008, 1129 : 141 - 152
  • [8] From the perception of action to the understanding of intention
    Blakemore, SJ
    Decety, J
    [J]. NATURE REVIEWS NEUROSCIENCE, 2001, 2 (08) : 561 - 567
  • [9] A modern learning theory perspective on the etiology of panic disorder
    Bouton, ME
    Mineka, S
    Barlow, DH
    [J]. PSYCHOLOGICAL REVIEW, 2001, 108 (01) : 4 - 32
  • [10] Different patterns of freezing behavior organized in the periaqueductal gray of rats: Association with different types of anxiety
    Brandao, Marcus L.
    Zanoveli, Janaina M.
    Ruiz-Martinez, Raquel C.
    Oliveira, Luciana C.
    Landeira-Fernandez, Jesus
    [J]. BEHAVIOURAL BRAIN RESEARCH, 2008, 188 (01) : 1 - 13
12345678