Acute post-streptococcal glomerulonephritis in a 14-month-old boy: why is this uncommon?

被引：13

作者：

Bingler, Michael A.

Ellis, Demetrius

Moritz, Michael L.

机构：

[1] Univ Pittsburgh, Sch Med, Childrens Hosp Pittsburgh, Div Nephrol, Pittsburgh, PA 15213 USA

[2] Univ Pittsburgh, Sch Med, Childrens Hosp Pittsburgh, Dept Pediat, Pittsburgh, PA 15213 USA

来源：

PEDIATRIC NEPHROLOGY | 2007年 / 22卷 / 03期

关键词：

glomerulonephritis; hematuria; proteinuria; streptococcus;

D O I：

10.1007/s00467-006-0337-6

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Acute post-streptococcal glomerulonephritis (APSGN) is rare in children under 2 years of age. This is related in part to the disease patterns of group A streptococcus (GAS) and in part to impaired immunogenicity in infants. We report the case of a 14-month-old child with APSGN following GAS pharyngitis. This case illustrates that APSGN needs to be considered in the evaluation of both gross and microscopic hematuria in this age group. We review the literature of both GAS and APSGN and discuss the pathogenesis and epidemiologic reasons for this association.

引用

页码：448 / 450

页数：3

共 16 条

[1] Neonatal adaptive immunity comes of age [J].