Oral or Topical 5-ASA in Ulcerative Colitis

被引：12

作者：

Hanauer, Stephen B. ^{[1
]}

机构：

[1] Northwestern Univ, Feinberg Sch Med, Med, Chicago, IL 60611 USA

来源：

DIGESTIVE DISEASES | 2016年 / 34卷 / 1-2期

关键词：

5-Aminosalicylic acid; Mesalamine; Mesalazine; Ulcerative colitis; DOUBLE-BLIND; EFFICACY; 5-AMINOSALICYLATES; MESALAMINE; MESALAZINE; INDUCTION; REMISSION; RELAPSE;

D O I：

10.1159/000443026

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Aminosalicylates (5-ASAs) are foundational therapies for patients with mild-moderate active ulcerative colitis (UC) and to maintain remissions. A variety of oral and topical formulations have been evaluated in both active and quiescent disease in both extensive and distal UC. This review summarizes data on pharmacokinetics and applications of oral and topical 5-ASA therapies in active and quiescent, extensive colitis and distal disease, both as monotherapies and in combination and reviews dosing and dosing intervals for oral 5-ASA in both active disease and to maintain remissions. (C) 2016 S. Karger AG, Basel

引用

页码：122 / 124

页数：3

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