Thermal behavior of inosine 5′-monophosphate complexes with cobalt(II), nickel(II), copper(II) and cadmium(II) cations

被引：4

作者：

de Jesus, J. H. F. ^{[1
]}

Souza, M. S. ^{[2
]}

Ellena, J. A. ^{[2
]}

Cavalheiro, E. T. G. ^{[1
]}

机构：

[1] Univ Sao Paulo, Inst Quim Sao Carlos, Ave Trabalhador Sao Carlense 400, BR-13566590 Sao Carlos, SP, Brazil

[2] Univ Sao Paulo, Inst Fis Sao Carlos, Ave Trabalhador Sao Carlense 400, BR-13566590 Sao Carlos, SP, Brazil

来源：

THERMOCHIMICA ACTA | 2019年 / 680卷

基金：

巴西圣保罗研究基金会;

关键词：

Inosine 5 '-monophosphate; Thermal analysis; Evolved gas analysis; IMP-Cd(II) structure; X-RAY EVIDENCE; CRYSTAL-STRUCTURES; METAL-IONS; NUCLEOTIDES; BINDING; 5-MONOPHOSPHATE; PLATINUM(II); ALKALI; SALT; N(7);

D O I：

10.1016/j.tca.2019.178378

中图分类号：

O414.1 [热力学];

学科分类号：

摘要：

Interaction of nucleotides and metals has been largely studied since they have biological importance. Divalent complexes of inosine 5'-monophosphate with cobalt(II) (IMP-Co), nickel(11) (IMP-Ni), copper(II) (IMP-Cu) and cadmium(II) (IMP-Cd) have been characterized by elemental analysis and submitted to thermogravimetry (TG), differential thermal analysis (DTA), differential scanning calorimetry (DSC) and thermogravimetry coupled to infrared spectroscopy (TG-FTIR). Cadmium(II) complex with inosine 5'-monophosphate had also its crystalline structure elucidated by single-crystal X-ray diffraction. Elemental analysis revealed that the isolated metal complexes presented a 1:1 stoichiometry. The thermal stability order was: IMP-Co (193 degrees C) = IMP-Cd (193 degrees C) < IMP-Ni (206 degrees C) < IMP-Cu (219 degrees C), after dehydration. Cd2+ ions present octahedral coordination with an IMP ligand through nitrogen donor atom and the remaining coordinating sites through five water molecules. The crystal packing assembly has a similar distribution to the DNA molecule, with alternation between the atoms leading to a helical conformation.

引用

页数：7

共 23 条

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