Hypoalbuminemia at admission is associated with increased incidence of in-hospital complications in geriatric trauma patients

被引:39
作者
Garwe, Tabitha [1 ,2 ]
Albrecht, Roxie M. [1 ]
Stoner, Julie A. [2 ]
Mitchell, Stephanie [1 ]
Motghare, Prasenjeet [2 ]
机构
[1] Univ Oklahoma, Hlth Sci Ctr, Dept Surg, Oklahoma City, OK USA
[2] Univ Oklahoma, Hlth Sci Ctr, Dept Biostat & Epidemiol, 801 NE 13th St, Oklahoma City, OK 73104 USA
关键词
Hypoalbuminemia; Protein-energy malnutrition; Geriatric trauma; In-hospital; Complications; SERUM-ALBUMIN LEVEL; NUTRITION SUPPORT; PREDICTOR; MALNUTRITION; MARKERS; INJURY; RISK;
D O I
10.1016/j.amjsurg.2015.06.013
中图分类号
R61 [外科手术学];
学科分类号
摘要
BACKGROUND: Elderly patients are at an increased risk of protein-energy malnutrition (PEM) which increases the risk of morbidity/mortality. We evaluated the association between hypoalbuminemia at the time of emergency department (ED) admission and in-hospital complications among geriatric trauma patients. METHODS: This was an ambidirectional cohort study of geriatric (>= 55 years) trauma patients treated at a Level I trauma center between May 2013 and March 2014. The exposure of interest was albumin level at ED admission (<3.6 g/dL [PEM] or >= 3.6 g/dL (No PEM)]. The outcome of interest was 30-day incidence of complications. RESULTS: A total of 130 patients met study eligibility. Of these, 85 (65%) patients were in the PEM group. After adjusting for tube feeding and injury severity score, PEM at admission was associated with a 2-fold increase in the risk of 30-day overall hospital complications (hazard ratio 2.1, 95% confidence interval 1.1 to 3.8). CONCLUSION: Serum albumin level at ED admission, but not prealbumin level, is a significant predictor of in-hospital complications in geriatric trauma patients. (C) 2015 Elsevier Inc. All rights reserved.
引用
收藏
页码:109 / 115
页数:7
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