5-Lipoxygenase:: Regulation and possible involvement in atherosclerosis

被引：64
|
作者：
Radmark, Olof [1 ]
Samuelsson, Bengt [1 ]
机构：
[1] Karolinska Inst, Div Physiol Chem 2, Dept Med Biochem & Biophys, S-17177 Stockholm, Sweden
来源：
PROSTAGLANDINS & OTHER LIPID MEDIATORS | 2007年 / 83卷 / 03期
关键词：
leukotriene; eicosanoid; arachidonic acid; inflammation;
D O I：
10.1016/j.prostaglandins.2007.01.003
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
This review article focuses on two aspects regarding 5-lipoxygenase. First, mechanisms for activation of the enzyme. Second, the involvement of 5-lipoxygenase and leukotrienes in atherosclerosis. (C) 2007 Elsevier Inc. All rights reserved.
引用
收藏
页码：162 / 174
页数：13
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