Topical chemotherapy for ocular surface squamous neoplasia: current status

被引：43
作者：
Sepulveda, Ricardo
Pe'er, Jacob [2 ]
Midena, Edoardo [3 ]
Seregard, Stefan [4 ]
Dua, Harminder S. [5 ]
Singh, Arun D. [1 ]
机构：
[1] Cleveland Clin, Cole Eye Inst, Dept Ophthalm Oncol, 9500 Euclid Ave, Cleveland, OH 44195 USA
[2] Hadassah Univ Hosp, Dept Ophthalmol, IL-91120 Jerusalem, Israel
[3] Univ Padua, Dept Ophthalmol, Padua, Italy
[4] Karolinska Univ, St Eriks Eye Hosp, Stockholm, Sweden
[5] Univ Nottingham, Div Ophthalmol & Visual Sci, Nottingham NG7 2RD, England
来源：
BRITISH JOURNAL OF OPHTHALMOLOGY | 2010年 / 94卷 / 05期
关键词：
CORNEAL INTRAEPITHELIAL NEOPLASIA; TERM-FOLLOW-UP; MITOMYCIN-C; CLINICAL-APPLICATIONS; EPITHELIAL DYSPLASIA; CONJUNCTIVAL; 5-FLUOROURACIL; INTERFERON; PROLIFERATION; FLUOROURACIL;
D O I：
10.1136/bjo.2009.160820
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
Although there are no randomised trials directly comparing topical chemotherapeutic agents mitomycin-C, 5-fluorouracil, and interferon-alpha 2b, published studies indicate equal efficacy of these agents for treatment of non-invasive ocular surface squamous neoplasia (80%-88%). 5-Fluorouracil may be preferred, given low incidence of serious side effects and low cost to the patient.
引用
收藏
页码：532 / 535
页数：4
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