Removal of diclofenac sodium from aqueous solution using water/Transcutol/ethylene glycol/Capryol-90 green nanoemulsions

被引:14
作者
Shakeel, Faiyaz [1 ]
Haq, Nazrul [1 ]
Ahmed, Mohammed A. [1 ]
Gambhir, Dikshit [1 ]
Alanazi, Fars K. [1 ,2 ]
Alsarra, Ibrahim A. [1 ,2 ]
机构
[1] King Saud Univ, Coll Sci, Ctr Excellence Biotechnol Res, Riyadh 11451, Saudi Arabia
[2] King Saud Univ, Coll Pharm, Dept Pharmaceut, Riyadh 11451, Saudi Arabia
关键词
Adsorption; Diclofenac sodium; Droplet size; Green nanoemulsion; Capiyol-90; PERSONAL CARE PRODUCTS; WASTE-WATER TREATMENT; ACIDIC PHARMACEUTICALS; ELIMINATION; KINETICS; SYSTEM; IMPACT; DRUGS; FATE; RAW;
D O I
10.1016/j.molliq.2014.08.030
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
In the present investigation, attempts were made to develop water/Transcutol/ethylene glycol (EG)/Capryol-90 green nanoemulsions for the removal of diclofenac sodium (DS) from aqueous solution. Various green nanoemulsions were prepared by oil phase titration method. Removal of DS was influenced by Capryol-90 & water concentrations, droplet size and viscosity. Based on lowest droplet size (43.6 nm), lowest viscosity (81.4 cP) and highest % removal (94.5%), the green nanoemulsion G(5) containing 20% w/w of water, 50% w/w of surfactant mixture and 30% w/w of Capryol-90 was selected as an optimized formulation for the removal of DS from aqueous solution. (C) 2014 Elsevier B.V. All rights reserved.
引用
收藏
页码:102 / 107
页数:6
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