Age-related inflammatory cytokines and disease

被引：467
作者：
Brüünsgaard, H
Pedersen, BK
机构：
[1] Univ Copenhagen, Rigshosp, Dept Infect Dis M7641, DK-2100 Copenhagen, Denmark
[2] Univ Copenhagen, Rigshosp, Copenhagen Muscle Res Ctr, DK-2100 Copenhagen, Denmark
来源：
IMMUNOLOGY AND ALLERGY CLINICS OF NORTH AMERICA | 2003年 / 23卷 / 01期
关键词：
D O I：
10.1016/S0889-8561(02)00056-5
中图分类号：
R392 [医学免疫学];
学科分类号：
100102 ;
摘要：
Studies have demonstrated that circulating levels of plasma cytokines are influenced greatly by age and that chronic elevated levels of certain cytokines are associated with chronic diseases. This article discusses the origin of age-associated elevations in circulating levels of cytokines, focusing on the multifunctional tumor necrosis factor alpha (TNF-alpha) and interleukin 6 (IL-6) and their possible biologic effects in age-associated diseases.
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页码：15 / +
页数：26
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