In vitro studies of inflammation and contact activation of titanium oxide film

被引：0

作者：

Zhao, Ansha ^{[1
]}

Yang, Ping ^{[1
]}

Leng, YongXiang ^{[1
]}

Chen, Junying ^{[1
]}

Wang, Jin ^{[1
]}

Wan, Guojiang ^{[1
]}

Huang, Nan ^{[1
]}

机构：

[1] Southwest Jiaotong Univ, Sch Mat & Engn, Chengdu 610031, Peoples R China

来源：

BIOCERAMICS, VOL 19, PTS 1 AND 2 | 2007年 / 330-332卷

关键词：

titanium oxide; macrophage; contact activation; MCP-1;

D O I：

10.4028/www.scientific.net/KEM.330-332.729

中图分类号：

TQ174 [陶瓷工业]; TB3 [工程材料学];

学科分类号：

0805 ; 080502 ;

摘要：

Ti-O film is a kind of potential biornaterial may be applied in medical devices. But the mechanism of its good biocompatility is not so clear. This study revealed that when Titanium oxide contact with macrophage and plasma, the activation, adhesion and secretion of inflammatory molecule MCP-1 of macrophage is lower than reference material. Ti-O film also show minor contact activation to plasma. So reducing the host reaction including contact activation and inflammation may be the important reason for the good biocompatibility of Ti-O film.

引用

页码：729 / +

页数：2

共 9 条

[1]

ANDERSON JM, 1984, BIOMATERIALS, V5, P5, DOI 10.1016/0142-9612(84)90060-7

[2] MOLECULAR IMMUNOBIOLOGY OF MACROPHAGES - RECENT PROGRESS [J].

GORDON, S ;

CLARKE, S ;

GREAVES, D ;

DOYLE, A .

CURRENT OPINION IN IMMUNOLOGY, 1995, 7 (01) :24-33

[3] Hemocompatibility of titanium oxide films [J].

Huang, N ;

Yang, P ;

Leng, YX ;

Chen, JY ;

Sun, H ;

Wang, J ;

Wang, GJ ;

Ding, PD ;

Xi, TF ;

Leng, Y .

BIOMATERIALS, 2003, 24 (13) :2177-2187

[4]

Sittig C, 1999, J MATER SCI-MATER M, V10, P35, DOI 10.1023/A:1008840026907

[5] City and language in the thought of Carlo Cattaneo [J].

Thom, M .

JOURNAL OF MODERN ITALIAN STUDIES, 2000, 5 (01) :1-21

[6] CONTACT ACTIVATION OF THE PLASMA COAGULATION CASCADE .1. PROCOAGULANT SURFACE-CHEMISTRY AND ENERGY [J].

VOGLER, EA ;

GRAPER, JC ;

HARPER, GR ;

SUGG, HW ;

LANDER, LM ;

BRITTAIN, WJ .

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH, 1995, 29 (08) :1005-1016

[7] TITANIUM WITH DIFFERENT OXIDES - IN-VITRO STUDIES OF PROTEIN ADSORPTION AND CONTACT ACTIVATION [J].

WALIVAARA, B ;

ARONSSON, BO ;

RODAHL, M ;

LAUSMAA, J ;

TENGVALL, P .

BIOMATERIALS, 1994, 15 (10) :827-834

[8] Inhibition of adherent platelet activation produced by Ti-O thin film fabricated by PIII [J].

Yang, P ;

Huang, N ;

Leng, YX ;

Chen, JY ;

Sun, H ;

Wang, J ;

Wan, GJ .

SURFACE & COATINGS TECHNOLOGY, 2004, 186 (1-2) :265-269

[9] In vivo study of Ti-O thin film fabricated by PIII [J].

Yang, P ;

Huang, N ;

Leng, YX ;

Chen, JY ;

Sun, H ;

Wang, J ;

Chen, F ;

Chu, PK .

SURFACE & COATINGS TECHNOLOGY, 2002, 156 (1-3) :284-288

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