Will polygenic risk scores for cancer ever be clinically useful?

被引：39
|
作者：
Sud, Amit [1 ]
Turnbull, Clare [1 ]
Houlston, Richard [1 ]
机构：
[1] Inst Canc Res, Div Genet & Epidemiol, London, England
来源：
NPJ PRECISION ONCOLOGY | 2021年 / 5卷 / 01期
基金：
英国惠康基金;
关键词：
GENOME-WIDE ASSOCIATION; COLORECTAL-CANCER; PROSTATE-CANCER; SUSCEPTIBILITY; IMPACT; MEN;
D O I：
10.1038/s41698-021-00176-1
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页数：5
相关论文
共 50 条
  • [1] Polygenic Risk Scores in Prostate Cancer Risk Assessment and Screening
    Byrne, Lindsey
    Toland, Amanda Ewart
    UROLOGIC CLINICS OF NORTH AMERICA, 2021, 48 (03) : 387 - 399
  • [2] Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes
    Mavaddat, Nasim
    Michailidou, Kyriaki
    Dennis, Joe
    Lush, Michael
    Fachal, Laura
    Lee, Andrew
    Tyrer, Jonathan P.
    Chen, Ting-Huei
    Wang, Qin
    Bolla, Manjeet K.
    Yang, Xin
    Adank, Muriel A.
    Ahearn, Thomas
    Aittomaki, Kristiina
    Allen, Jamie
    Andrulis, Irene L.
    Anton-Culver, Hoda
    Antonenkova, Natalia N.
    Arndt, Volker
    Aronson, Kristan J.
    Auer, Paul L.
    Auvinen, Paivi
    Barrdahl, Myrto
    Freeman, Laura E. Beane
    Beckmann, Matthias W.
    Behrens, Sabine
    Benitez, Javier
    Bermisheva, Marina
    Bernstein, Leslie
    Blomqvist, Carl
    Bogdanova, Natalia, V
    Bojesen, Stig E.
    Bonanni, Bernardo
    Borresen-Dale, Anne-Lise
    Brauch, Hiltrud
    Bremer, Michael
    Brenner, Hermann
    Brentnall, Adam
    Brock, Ian W.
    Brooks-Wilson, Angela
    Brucker, Sara Y.
    Bruening, Thomas
    Burwinkel, Barbara
    Campa, Daniele
    Carter, Brian D.
    Castelao, Jose E.
    Chanock, Stephen J.
    Chlebowski, Rowan
    Christiansen, Hans
    Clarke, Christine L.
    AMERICAN JOURNAL OF HUMAN GENETICS, 2019, 104 (01) : 21 - 34
  • [3] Could Polygenic Risk Scores Be Useful in Psychiatry? A Review
    Murray, Graham K.
    Lin, Tian
    Austin, Jehannine
    McGrath, John J.
    Hickie, Ian B.
    Wray, Naomi R.
    JAMA PSYCHIATRY, 2021, 78 (02) : 210 - 219
  • [4] Assessing thyroid cancer risk using polygenic risk scores
    Liyanarachchi, Sandya
    Gudmundsson, Julius
    Ferkingstad, Egil
    He, Huiling
    Jonasson, Jon G.
    Tragante, Vinicius
    Asselbergs, Folkert W.
    Xu, Li
    Kiemeney, Lambertus A.
    Netea-Maier, Romana T.
    Mayordomo, Jose I.
    Plantinga, Theo S.
    Hjartarson, Hannes
    Hrafnkelsson, Jon
    Sturgis, Erich M.
    Brock, Pamela
    Nabhan, Fadi
    Thorleifsson, Gudmar
    Ringel, Matthew D.
    Stefansson, Kari
    de la Chapelle, Albert
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2020, 117 (11) : 5997 - 6002
  • [5] Polygenic Risk Scores in Breast Cancer
    Mina, Lida A.
    Arun, Banu
    CURRENT BREAST CANCER REPORTS, 2019, 11 (03) : 117 - 122
  • [6] Are polygenic risk scores ready for the cancer clinic?-a perspective
    Klein, Robert J.
    Gumus, Zeynep H.
    TRANSLATIONAL LUNG CANCER RESEARCH, 2022, 11 (05) : 910 - 919
  • [7] Power and Predictive Accuracy of Polygenic Risk Scores
    Dudbridge, Frank
    PLOS GENETICS, 2013, 9 (03):
  • [8] Polygenic risk scores in schizophrenia with clinically significant copy number variants
    Taniguchi, Satoru
    Ninomiya, Kohei
    Kushima, Itaru
    Saito, Takeo
    Shimasaki, Ayu
    Sakusabe, Takaya
    Momozawa, Yukihide
    Kubo, Michiaki
    Kamatani, Yoichiro
    Ozaki, Norio
    Ikeda, Masashi
    Iwata, Nakao
    PSYCHIATRY AND CLINICAL NEUROSCIENCES, 2020, 74 (01) : 35 - 39
  • [9] Evaluating Polygenic Risk Scores for Breast Cancer in Women of African Ancestry
    Du, Zhaohui
    Gao, Guimin
    Adedokun, Babatunde
    Ahearn, Thomas
    Lunetta, Kathryn L.
    Zirpoli, Gary
    Troester, Melissa A.
    Ruiz-Narvaez, Edward A.
    Haddad, Stephen A.
    PalChoudhury, Parichoy
    Figueroa, Jonine
    John, Esther M.
    Bernstein, Leslie
    Zheng, Wei
    Hu, Jennifer J.
    Ziegler, Regina G.
    Nyante, Sarah
    Bandera, Elisa, V
    Ingles, Sue A.
    Mancuso, Nicholas
    Press, Michael F.
    Deming, Sandra L.
    Rodriguez-Gil, Jorge L.
    Yao, Song
    Ogundiran, Temidayo O.
    Ojengbe, Oladosu
    Bolla, Manjeet K.
    Dennis, Joe
    Dunning, Alison M.
    Easton, Douglas F.
    Michailidou, Kyriaki
    Pharoah, Paul D. P.
    Sandler, Dale P.
    Taylor, Jack A.
    Wang, Qin
    Weinberg, Clarice R.
    Kitahara, Cari M.
    Blot, William
    Nathanson, Katherine L.
    Hennis, Anselm
    Nemesure, Barbara
    Ambs, Stefan
    Sucheston-Campbell, Lara E.
    Bensen, Jeannette T.
    Chanock, Stephen J.
    Olshan, Andrew F.
    Ambrosone, Christine B.
    Olopade, Olufunmilayo, I
    Yarney, Joel
    Awuah, Baffour
    JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2021, 113 (09): : 1168 - 1176
  • [10] Evaluation of Polygenic Risk Scores for Prediction of Prostate Cancer in Korean Men
    Oh, Jong Jin
    Kim, Eunae
    Woo, Eunjin
    Song, Sang Hun
    Kim, Jung Kwon
    Lee, Hakmin
    Lee, Sangchul
    Hong, Sung Kyu
    Byun, Seok-Soo
    FRONTIERS IN ONCOLOGY, 2020, 10
12345