Subtyping method for Escherichia coli Shiga toxin (verocytotoxin) 2 variants and correlations to clinical manifestations

被引:240
作者
Persson, Soren
Olsen, Katharina E. P.
Ethelberg, Steen
Scheutz, Flemming
机构
[1] Statens Serum Inst, Dept Bacteriol Mycol & Parasitol, Natl Reference Lab Enteropathogen Bacteria, Unit Gastrointestinal Infect, DK-2300 Copenhagen S, Denmark
[2] Statens Serum Inst, Int Escherichia & Klebsiella Ctr, WHO, Unit Gastrointestinal Infect, DK-2300 Copenhagen, Denmark
关键词
D O I
10.1128/JCM.02591-06
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Shiga toxin 2 (Stx2) from Shiga toxin-producing Escherichia coli (STEC) was subtyped by a method involving partial sequencing of the stxAB(2) operon. Of 255 strains from the Danish STEC cohort, all 20 cases of hemolytic-uremic syndrome were associated with subtype Stx2 (11 cases), subtype Stx2c (1 case), or the two combined (8 cases).
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页码:2020 / 2024
页数:5
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